Results 141 to 150 of about 2,935,830 (275)

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in <i>Giardia lamblia</i>. [PDF]

Microbiol Spectr, 2023
Kim J, Park EA, Shin MY, Park SJ.
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Targeting cyclin-dependent kinases in sarcoma treatment: Current perspectives and future directions. [PDF]

Front Oncol, 2023
Merlini A, Pavese V, Manessi G, Rabino M, Tolomeo F, Aliberti S, D'Ambrosio L, Grignani G.   +7 more
europepmc   +1 more source

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

Chemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee   +5 more
wiley   +1 more source

Cyclins and Cyclin-Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer. [PDF]

MedComm (2020)
Zheng S, Shen Z, Wu Y, Huang X, Zhang Z, Liu J, Wei Q, Chen W, Chen Y, Xu L.   +9 more
europepmc   +1 more source

Focusing on cyclin-dependent kinases 5: A potential target for neurological disorders. [PDF]

Front Mol Neurosci, 2022
Tian Z, Feng B, Wang XQ, Tian J.
europepmc   +1 more source

Creatinine–Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib

Clinical Pharmacology &Therapeutics, EarlyView.
Abemaciclib increases serum creatinine by inhibiting renal tubular transporters rather than reducing true glomerular filtration rate, a phenomenon known as pseudo‐acute kidney injury. Creatinine–cystatin C discrepancy and genetic determinants of this elevation remain insufficiently characterized in Japanese patients.
Hiroaki Watanabe, Keita Hirai, Takaaki Oba, Mayu Ono, Ken‐ichi Ito, Takafumi Naito   +5 more
wiley   +1 more source

Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen

Developmental Dynamics, EarlyView.
Abstract Background One of the most characteristic morphogenetic processes in Drosophila is the 360° rotation of the male pupal genital disc. This movement is driven by the myosin Myo1D, whose expression in the genital disc is controlled by the Hox gene Abdominal‐B (Abd‐B).
Nuria Prieto, David Foronda, Paloma Martín, Eléanor Simon, Marcus Bischoff, Stéphane Noselli, Ernesto Sánchez‐Herrero   +6 more
wiley   +1 more source

Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes. [PDF]

Viruses, 2023
Kokinos EK, Tsymbal SA, Galochkina AV, Bezlepkina SA, Nikolaeva JV, Vershinina SO, Shtro AA, Tatarskiy VV, Shtil AA, Broude EV, Roninson IB, Dukhinova M.   +11 more
europepmc   +1 more source

The Emerging Role of Transcription-Associated Cyclin-Dependent Kinases in Gastrointestinal Tumors. [PDF]

Cancers (Basel)
Athavale D, Pulipati D, Balch C, Zhao J, Zhang Y, Yao X, Song S.   +6 more
europepmc   +1 more source