Results 61 to 70 of about 3,178,268 (185)

Reactivation of the mitosis-promoting factor in postmitotic cardiomyocytes [PDF]

, 2003
Cardiomyocytes cease to divide shortly after birth and an irreversible cell cycle arrest is evident accompanied by the downregulation of cyclin-dependent kinase activities.
Datwyler, D. A., Weikert, C., Wightman, L., Magyar, J. P., Hans M. Eppenberger, Wagner, E., Eppenberger, H. M., Josef P. Magyar, Lionel Wightman, Daniel A. Dätwyler, Ernst Wagner, Christian Weikert, Wagner E, Eppenberger HM, Magyar JP, Wightman L, Dätwyler DA, Weikert C   +17 more
core   +1 more source

Il ciclo cellulare: cos'è, come è stato e come sarà studiato

Giornale di Clinica Nefrologia e Dialisi, 2015
non ...
Sara Nardi, Duccio Lombardi
doaj   +1 more source

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain

Viruses, 2015
Replication of human cytomegalovirus (HCMV) is characterized by a tight virus-host cell interaction. Cyclin-dependent protein kinases (CDKs) are functionally integrated into viral gene expression and protein modification.
Mirjam Steingruber, Eileen Socher, Corina Hutterer, Rike Webel, Tim Bergbrede, Tihana Lenac, Heinrich Sticht, Manfred Marschall   +7 more
doaj   +1 more source

Cyclin C: The Story of a Non-Cycling Cyclin

Biology, 2019
The class I cyclin family is a well-studied group of structurally conserved proteins that interact with their associated cyclin-dependent kinases (Cdks) to regulate different stages of cell cycle progression depending on their oscillating expression ...
Jan Ježek, Daniel G. J. Smethurst, David C. Stieg, Z. A. C. Kiss, Sara E. Hanley, Vidyaramanan Ganesan, Kai-Ti Chang, Katrina F. Cooper, Randy Strich   +8 more
doaj   +1 more source

Structural dissection of cyclin dependent kinases regulation and protein recognition properties.

, 2010
Cyclin Dependent Kinases (CDKs) regulate the cell division cycle, apoptosis, transcription and differentiation in addition to functions in the nervous system.
LOLLI, GRAZIANO, Graziano Lolli
core   +1 more source

A cell cycle-regulated inhibitor of cyclin-dependent kinases

, 1994
International audienceCyclin-dependent kinases (Cdks) previously have been shown to drive the major cell cycle transitions in eukaryotic organisms ranging from yeast to humans.
Hengst, L, Slingerland, J, Slingerland, J M, Dulic, V, Reed, S I, Dulic, Vjekoslav, Reed, S, Lees, E   +7 more
core   +1 more source

Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]

, 2014
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic ...
Jaiswal, H., Mullers, E, Cascales, H.S., Cascales, HS, Lindqvist, A., Jaiswal, H, Saurin, AT, Lindqvist, A,, Müllers, E., Saurin, A.T.; id_orcid   +9 more
core   +1 more source

Interplay between CKS2, N-cadherin, and PD-ECGF in Non-Schistosomal and Schistosomal-Associated Bladder Cancer: A Prospective Comparative Study in the Egyptian Population

Middle East Journal of Cancer, 2017
Background: The current study investigated the possible role of the cell cycle regulator, cyclin-dependent kinases regulatory subunit-2; the angiogenic factor, plateletderived endothelial cell growth factor; and the cell adhesive molecule, neural ...
Sanaa Shawky, Mona Salem, Hoda Abou Seif, Salah El Din El Salmy, Manal Sheta, Eman El-Abd   +5 more
doaj  

Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1

, 2000
A series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin dependent kinases (CDKs).
Laurent Meijer, Ji Hong Ha, Ji-Hong Ha, Ha Won Jeong, Kwang-Hee Son, Ha-Won Jeong, Mi Young Han, Byoung-Mog Kwon, Mi Ran Kim, Kwang Hee Son, Mi-Ran Kim, Matthieu Garnier   +11 more
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Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts [PDF]

, 1992
. In eukaryotic ells, the onset of mitosis in-volves cyclin molecules which interact with proteins of the cdc2 family to produce active kinases. In verte-brate cells, cyclin A dependent kinases become active in S- and pro-phases, whereas a cyclin B ...
Eric Karsenti, Dogterom, M, Leibler, S, S Leibler, E Karsenti, Fulvia Verde, M Dogterom, Stanislas Leibler, Stelzer, E, Karsenti, E, F Verde, Ernst Stelzer, E Stelzer, Mari Leen Dogterom, Verde, F   +14 more
core   +1 more source