Results 161 to 170 of about 230,940 (319)
Animal Models and Experimental Medicine, EarlyView.Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai +7 more
wiley +1 more source
Emerging concepts in cancer therapy: Mechanisms of resistance
, 2022 Cancer Reports, Volume 5, Issue 12, December 2022.
Seema Gupta +2 more
wiley +1 more source
Angewandte Chemie, EarlyView.Die Erzeugung funktionalisierter Ubiquitinbausteine mittels Expression in E. coli bietet Zugang zu verschiedenen Di‐, Tri‐ und Tetra‐Ubiquitinketten. Photoinitiierte Thiol‐En‐Klickreaktionen werden dabei in Kombination mit einer Maskierungs‐ und Schutzgruppenstrategie zum kontrollierten Aufbau von Ubiquitinketten sowie zur Semisynthese von ...
Moritz Urschbach +6 more
wiley +1 more source
Isolation and characterization of cDNA clones for plant cyclins. [PDF]
, 1991 Shingo Hata +3 more
openalex +1 more source
Angewandte Chemie International Edition, EarlyView.Generating functionalized ubiquitin building blocks via expression in E. coli paves the way to different di‐, tri‐, and tetra‐ubiquitin chains. Light‐induced thiol‐ene click reactions, combined with a masking and protection strategy, are harnessed to establish controlled ubiquitin chain assembly and to allow the semisynthesis of site‐selectively ...
Moritz Urschbach +6 more
wiley +1 more source
Alcohol extracts of Chinese bayberry branch induce S‐phase arrest and apoptosis in HepG2 cells
Food Science &Nutrition, Volume 11, Issue 1, Page 493-503, January 2023., 2023 The alcohol extracts of Chinese bayberry Myrica rubra branches (MRBE) effectively inhibited the proliferation of HepG2 cells by inducing cell cycle arrest in S phase and promoting apoptosis, with this arrest potentially mediated by the activation of p21–Cyclin–CDK (cyclin‐dependent kinase) complex signaling pathways.
Yuanyuan Zheng +8 more
wiley +1 more source
Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. [PDF]
, 1994 Kevin D. Brown +3 more
openalex +1 more source
Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis
Arthritis &Rheumatology, EarlyView.Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott +14 more
wiley +1 more source
Genes, Chromosomes and Cancer, Volume 62, Issue 2, Page 93-100, February 2023., 2023 Abstract Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkpoint machinery.
Natalie Andersson +6 more
wiley +1 more source
Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components. [PDF]
, 1990 Pierre Pondaven +2 more
openalex +1 more source