Results 191 to 200 of about 230,940 (319)

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan   +13 more
wiley   +1 more source

Repression of cyclin D1: a novel function of MYC.

open access: green, 1994
A Philipp   +7 more
openalex   +1 more source

Immunohistochemical Analysis of Cyclin D1 Protein in Hematopoietic Neoplasms with Special Reference to Mantle Cell Lymphoma [PDF]

open access: hybrid, 1994
Shigeo Nakamura   +13 more
openalex   +1 more source

An open‐label, single‐arm, multicenter, phase II trial of bireociclib as monotherapy for heavily pretreated HR‐positive, HER2‐negative advanced breast cancer patients: BRIGHT‐1 trial

open access: yesCancer Communications, EarlyView.
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang   +18 more
wiley   +1 more source

A case of squamous cell carcinoma arising from a suprapubic cystostomy tract in a patient with spinal bifida: Immunohistochemical analysis and literature review

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 60-64, January 2023., 2023
Introduction Squamous cell carcinoma arising from a suprapubic cystostomy tract is a rare complication of an indwelling catheter and is caused by long‐term inflammation and mechanical irritation. Prognosis is relatively poor. Biomarkers in the cancer pathway have not been investigated.
Harutake Sawazaki   +4 more
wiley   +1 more source

Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.

open access: hybrid, 1991
Avram Hershko   +4 more
openalex   +1 more source

Simian virus 40 large T antigen associates with cyclin A and p33cdk2 [PDF]

open access: bronze, 1993
J P Adamczewski, Julian Gannon, Tim Hunt
openalex   +1 more source

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