Results 151 to 160 of about 240,615 (263)

Cyclins and Cyclin-Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer. [PDF]

MedComm (2020)
Zheng S, Shen Z, Wu Y, Huang X, Zhang Z, Liu J, Wei Q, Chen W, Chen Y, Xu L.   +9 more
europepmc   +1 more source

Exploring medical food supplementation as an adjunct strategy for microbiota restoration and seizure reduction in CDKL5 deficiency disorder

Epilepsia Open, EarlyView.
Abstract Objectives CDKL5 deficiency disorder (CDD) is a developmental and epileptic encephalopathy characterized by early‐onset, treatment‐resistant seizures and severe neurodevelopmental impairment. Increasing evidence suggests that alterations in the gut–brain axis may contribute to disease pathophysiology, raising interest in microbiota‐targeted ...
Elisa Borghi, Matteo Domenico Marsiglia, Francesca Triva, Emerenziana Ottaviano, Ilaria Viganò, Miriam Nella Savini, Valentino Costabile, Aglaia Vignoli   +7 more
wiley   +1 more source

Differential expression of cyclin D1 in pituitary neuroendocrine tumours: Relation to aggressive potential. [PDF]

Afr J Lab Med
Uchime KE, Awolola NA, Anunobi CC, Bankole OB, Banjo AA, Park SH.   +5 more
europepmc   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

The non-canonical CDK2 activator SPY1 uses separable mechanisms to activate phosphorylated and unphosphorylated CDK2. [PDF]

Biochem J
Fawcett LP, Levinson NM.
europepmc   +1 more source

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Correction: Cyclin B1 protects against meniscal extracellular matrix catabolism and degeneration via the NOD-like receptor pathway. [PDF]

Clin Sci (Lond)
Guan H, Cheng J, Yuan X, Cai D, Zhang H, Liu L.   +5 more
europepmc   +1 more source

Inhibition of CDK/Cyclin-phospho-Rb signaling by amebaciclib may have an antitumor effect against uterine leiomyosarcoma. [PDF]

Signal Transduct Target Ther
Hayashi T, Muto M, Konishi I.
europepmc   +1 more source

Correction: Pauzaite et al. Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway. <i>Biomedicines</i> 2022, <i>10</i>, 2012. [PDF]

Biomedicines
Pauzaite T, Tollitt J, Sopaci B, Caprani L, Iwanowytsch O, Thacker U, Hardy JG, Allinson SL, Copeland NA.   +8 more
europepmc   +1 more source

Acute abdominal presentation of mantle cell lymphoma mimicking acute appendicitis: a case report. [PDF]

J Surg Case Rep
Gray M, Oikonomou IM, Limbada M, Gourgiotis S.   +3 more
europepmc   +1 more source