Results 171 to 180 of about 345,409 (245)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Splenic Diffuse Red Pulp Small B-Cell Lymphoma with Overlapping Clinical and Immunophenotypic Features with Hairy Cell Leukaemia: A Case Report and a Review of the Literature. [PDF]

Genes (Basel)
Hanna M, Trus M, DiMaria E.
europepmc   +1 more source

Molecular subtyping and precision therapy for esophageal cancer

Interdisciplinary Medicine, EarlyView.
The molecular typing of esophageal cancer based on genome, transcriptome, proteome, and multi‐omics revealed various molecular features and provided potential targets for the precision therapy. Recent trials have shown that immunotherapy or molecular targeted therapy plus chemoradiotherapy can improve overall survival and progression‐free survival in ...
Guangkun Pei, Zhuoran Liang, Bianli Gu, Linlin Shi, Ze‐Xian Liu, Shegan Gao   +5 more
wiley   +1 more source

Secondary Metabolites from <i>Croton</i> Species and Their Biological Activity on Cell Cycle Regulators. [PDF]

Metabolites
Alamillo-Vásquez JA, Pérez-Torres CA, Ibarra-Laclette E, Ramón-Farías F, Nicasio-Torres P, Alatorre-Cobos F.   +5 more
europepmc   +1 more source

The discovery of cyclin (II)

Cell, 2004
openaire   +2 more sources

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells. [PDF]

PLoS One
Chen YC, Tsai WC, Li ZX, Lin WJ, Lin HY, Hsieh YJ, Wang KH, Chen YY, Hwang TL, Lin TY.   +9 more
europepmc   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

Cyclin Y interacts with Chk1 to activate RRM2/STAT3 signaling and promotes radioresistance in non-small cell lung cancer. [PDF]

Int J Biol Sci
Liu Z, Xue H, Wang Z, Zhao Y, Xu S, Dong X.   +5 more
europepmc   +1 more source

Inhibition of colorectal cancer cell growth by downregulation of M2-PK and reduction of aerobic glycolysis by clove active ingredients. [PDF]

Front Pharmacol
Liu L, Xing G, Guo X, Chen H, Li J, Wang J, Li Y, Liang G, Liu M.   +8 more
europepmc   +1 more source