Results 11 to 20 of about 12,781,724 (361)
Cyclin B and Cyclin A Confer Different Substrate Recognition Properties on CDK2 [PDF]
Cell Cycle, 2007 The transitions of the cell cycle are regulated by the cyclin dependent protein kinases (CDKs). The cyclins activate their respective CDKs and confer substrate recognition properties. We report the structure of phospho-CDK2/cyclin B and show that cyclin B confers M phase-like properties on CDK2, the kinase that is usually associated with S phase ...
N. Brown +5 more
semanticscholar +4 more sources
The Crystal Structure of Human Cyclin B [PDF]
Cell Cycle, 2007 Cyclin B is the key regulatory protein controlling mitosis in all eukaryotes, where it binds cyclin-dependent kinase, cdk1, forming a complex which initiates the mitotic program through phosphorylation of select proteins. Cyclin B regulates the activation, subcellular localization, and substrate specificity of cdk1, and destruction of cyclin B is ...
E. Petri +4 more
semanticscholar +3 more sources
Mip/LIN-9 Regulates the Expression of B-Myb and the Induction of Cyclin A, Cyclin B, and CDK1* [PDF]
Journal of Biological Chemistry, 2007 Members of the novel family of proteins that include Drosophila Mip130, Caenorhabditis elegans LIN-9, and mammalian LIN-9 intervene in different cellular functions such as regulation of transcription, differentiation, transformation, and cell cycle ...
M. Pilkinton +4 more
semanticscholar +3 more sources
Folia Histochemica et Cytobiologica, 2011 B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activation level, maturation state or cellular subgroups in peripheral blood.
Marzec-Kotarska Barbara +4 more
doaj +3 more sources
Both cyclin A delta 60 and B delta 97 are stable and arrest cells in M-phase, but only cyclin B delta 97 turns on cyclin destruction. [PDF]
EMBO Journal, 1991 Francis C. Luca +3 more
openalex +2 more sources
CDK-dependent nuclear localization of B-Cyclin Clb1 promotes FEAR activation during meiosis I in budding yeast [PDF]
, 2013 Cyclin-dependent kinases (CDK) are master regulators of the cell cycle in eukaryotes. CDK activity is regulated by the presence, post-translational modification and spatial localization of its regulatory subunit cyclin.
A Sourirajan +38 more
core +21 more sources
Proceedings of the National Academy of Sciences of the United States of America, 1991 Kathleen E. Steinmann +3 more
openalex +3 more sources
Activation of human B-MYB by cyclins [PDF]
Proceedings of the National Academy of Sciences, 1997 B-MYB expression is associated with cell proliferation and recent studies have suggested that it promotes the S phase of mammalian cells. Based on its homology to the transcription factors c-MYB and A-MYB, B-MYB is thought to be involved in transcriptional regulation; however, its activity is not detectable in several cell lines.
Sala A +10 more
openaire +5 more sources