Results 31 to 40 of about 13,222,515 (326)
BMC Complementary and Alternative Medicine, 2018 Background Although the inhibitory effect of mistletoe on cancer cell growth has been reported, the underlying mechanisms to explain its anti-proliferative activity are not fully studied.
Su Bin Park +7 more
doaj +1 more source
Carrying-over effects of GVBD blocking on post-blocking meiotic progression of oocytes: species difference and the signaling pathway leading to MPF activation. [PDF]
PLoS ONE, 2014 Efforts to improve the quality of in vitro matured oocytes by blocking germinal vesicle breakdown (GVBD) and allowing more time for ooplasmic maturation have achieved little due to a lack of knowledge on the molecular events during GVBD blocking.
Guang-Zhong Jiao +7 more
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Cyclin B–Cdk1 inhibits protein phosphatase PP2A-B55 via a Greatwall kinase–independent mechanism
Journal of Cell Biology, 2014 The role of Greatwall kinase in autoregulatory activation of cyclin B–Cdk1 at M phase onset can be bypassed by cyclin B–Cdk1–mediated direct phosphorylation of Arpp19, leading to PP2A-B55 inhibition.
E. Okumura +5 more
semanticscholar +1 more source
Characterization and localization of cyclin B3 transcript in both oocyte and spermatocyte of the rainbow trout (Oncorhynchus mykiss) [PDF]
PeerJ, 2019 B-type cyclins are regulatory subunits with distinct roles in the cell cycle. To date, at least three subtypes of B-type cyclins (B1, B2, and B3) have been identified in vertebrates. Previously, we reported the characterization and expression profiles of
Wenzhi Guan +5 more
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The ‘destruction box’ of cyclin A allows B-type cyclins to be ubiquitinated, but not efficiently destroyed. [PDF]
The EMBO Journal, 1996 The destruction of mitotic cyclins by programmed proteolysis at the end of mitosis is an important element in cell cycle control. This proteolysis depends on a conserved motif of nine residues known as the 'destruction box', which is located 40-50 residues from the N-terminus. The sequences of the A- and B-type destruction boxes are slightly different,
A Klotzbücher +3 more
openaire +3 more sources
Biomolecules, 2021 Botryococcus braunii produce liquid hydrocarbons able to be processed into combustion engine fuels. Depending on the growing conditions, the cell doubling time can be up to 6 days or more, which is a slow growth rate in comparison with other microalgae ...
Xochitl Morales-de la Cruz +6 more
doaj +1 more source
Phosphorylation of Crm1 by CDK1–cyclin-B promotes Ran-dependent mitotic spindle assembly
Journal of Cell Science, 2013 Summary Mitotic spindle assembly in animal cells is orchestrated by a chromosome-dependent pathway that directs microtubule stabilization. RanGTP generated at chromosomes releases spindle assembly factors from inhibitory complexes with importins, the ...
Zhige Wu +3 more
semanticscholar +1 more source
Distinct and Overlapping Requirements for Cyclins A, B, and B3 in Drosophila Female Meiosis
G3: Genes, Genomes, Genetics, 2016 Meiosis, like mitosis, depends on the activity of the cyclin dependent kinase Cdk1 and its cyclin partners. Here, we examine the specific requirements for the three mitotic cyclins, A, B, and B3 in meiosis of Drosophila melanogaster.
Mohammed Bourouh +5 more
doaj +1 more source
International Journal of Oncology, 2013 Kaempferol belongs to the flavonoid family and has been used in traditional folk medicine. Here, we investigated the antitumor effects of kaempferol on cell cycle arrest and autophagic cell death in SK-HEP-1 human hepatic cancer cells.
Wen-Wen Huang +8 more
semanticscholar +1 more source
A model for regulation of the cell cycle incorporating cyclin A, cyclin B and their complexes
Cell Proliferation, 1994 Abstract. t. A mathematical model for the cell cycle is proposed that incorporates the known biochemical reactions involving both cyclin A and cyclin B, the interactions of these cyclins with cdc2 and cdk2, and the controlling effects of cdc25 and weel.
Mandri N. Obeyesekere +2 more
openaire +3 more sources