Results 171 to 180 of about 152,964 (318)

Utilising Human Myometrial and Uterine Fibroid Stem Cell‐Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids

Cell Proliferation, EarlyView.
Three‐dimensional stem cell‐derived organoid model can serve as a robust platform to study the underlying molecular mechanisms of UFs, UFs health disparity, environmental risk factors, besides offering invaluable insights for potential therapeutic interventions.
Mervat M. Omran, Somayeh Vafaei, Samar Alkhrait, Farzana Liakath Ali, Maria Victoria Bariani, Tao Bai, Winston E. Thompson, Qiwei Yang, Mohamed Ali, Ayman Al‐Hendy   +9 more
wiley   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Abnormalities in thePRAD1 (CYCLIN D1 /BCL-1) oncogene are frequent in cervical and vulvar squamous cell carcinoma cell lines [PDF]

, 1995
Razelle Kurzrock, Stella Ku, Moshe Talpaz   +2 more
openalex   +1 more source

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbezylamine-induced rat esophageal tumorigenesis [PDF]

, 1996
Qian-Shu Wangu, Carol L. Sabourin, Hong Wang, Gary D. Stoner   +3 more
openalex   +1 more source

LncRNA H19‐Encoded Micropeptide altH19 Promotes DNA Replication and Mitosis in Myeloma Cells by Enhancing the Phosphorylation of CDK2 at Threonine 160

Cell Proliferation, EarlyView.
The micropeptide altH19 interacts with phosphorylated CDK2 (p‐CDK2), subsequently activating CDK2 phosphorylation. This enhances the downstream E2F1 target gene RB activity, which accelerates DNA replication, ultimately leading to rapid myeloma cell mitosis and proliferation.
Yaxin Zhang, Wenjing Li, Xu Cao, Jiwei Mao, Xiaodan Zhou, Linlin Liu, Ruosi Yao   +6 more
wiley   +1 more source

Role of cyclin D1 in breast carcinoma

Journal of Research in Medical Sciences, 2013
Background: Breast carcinoma is the most frequent cancer among women with considerable invasive and metastatic behavior. CCND1, the oncogene encoding cyclin D1, is amplified in a substantial proportion of human cancers.
Fereshteh Mohammadizadeh, Mohsen Hani, Mohammad Ranaee, Marzie Bagheri   +3 more
doaj  

Different Roles for Cyclins D1 and E in Regulation of the G₁-to-S Transition

, 1995
Dalia Resnitzky, Steven I. Reed
openalex   +1 more source

An Unusual Case of Cutaneous Langerhans Cell Sarcoma Lacking S100 Expression: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid, Austin R. Green, Sion W. Jasmine, Rachel P. Kowal, Brooj Abro, Laura M. Warmke, Magdalena B. Czader, Ahmed K. Alomari, Carina A. Dehner   +8 more
wiley   +1 more source

The t(11; 14) (q13; q32) in Multiple Myeloma Cell Line KMS12 has Its 11q13 Breakpoint 330 kb Centromeric From the Cyclin D1 Gene [PDF]

, 1997
Jan‐Willem Vaandrager, Philip M. Kluin, Ed Schuuring   +2 more
openalex   +1 more source