The impact of cyclin D1 on endometrial hyperplasia and endometrioid endometrial carcinoma
Introduction: Endometrioid endometrial carcinoma (EEC) is the most common type of endometrial cancer, accounting for approximately 80-90% of all endometrial cancer cases. Endometrial hyperplasia deserves special attention because of its relationship with
Sudha M, Shanmugapriya M, Vijay A
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Brucine Inhibits the Proliferation of Human Lung Cancer Cell Line PC-9 via Arresting Cell Cycle
Background and objective It has been proven that Cyclin D1 and Cyclin E are the important positive regulators of cell cycle, they are closely related to the tumor proliferation. The aim of this study is to explore the relationship between Brucine and the
Miao LI+4 more
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Background Mantle cell lymphoma is a clinically heterogeneous disease characterized by overexpression of cyclin D1 protein. Blastoid morphology, high proliferation, and secondary genetic aberrations are markers of aggressive behavior.
Julia Slotta-Huspenina+9 more
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Cyclin D1 expression in acute leukemia
Disorders of the cell cycle regulatory machinery play a key role in the pathogenesis of cancer. Over expression of cyclin D1 protein has been reported in several solid tumors and certain lymphoid malignancies, but little is known about the involvement of cyclin D1 in acute leukemia.In this study, we analyzed the expression of cyclin D1 at protein level
Mohamed Mabed+4 more
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Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. [PDF]
Dalia Resnitzky+3 more
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Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. [PDF]
Sharon Bodrug+5 more
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Immunohistochemical Analysis of Cyclin D1 Protein in Hematopoietic Neoplasms with Special Reference to Mantle Cell Lymphoma [PDF]
Shigeo Nakamura+13 more
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Transforming Potential of Dbl Family Proteins Correlates with Transcription from the Cyclin D1 Promoter but Not with Activation of Jun NH2-terminal Kinase, p38/Mpk2, Serum Response Factor, or c-Jun [PDF]
John Westwick+6 more
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Purification, Characterization, and Kinetic Mechanism of Cyclin D1·CDK4, a Major Target for Cell Cycle Regulation [PDF]
Alexandros K. Konstantinidis+4 more
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Background: nasopharyngeal cancer (NPC) is the most common type of head and neck cancer in Indonesia (28.4%). Reports showed that 18.9% of cases came with advanced stage. Chemotherapy play important role in advanced stage. However, patients with the same
Cosphiadi Irawan+4 more
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