Results 81 to 90 of about 250,304 (196)

Cyclin D1 regulates hepatic estrogen and androgen metabolism [PDF]

, 2010
Mullany LK, Hanse EA, Romano A, Blomquist CH, Mason JI, Delvoux B, Anttila C, Albrecht JH. Cyclin D1 regulates hepatic estrogen and androgen metabolism. Am J Physiol Gastrointest Liver Physiol 298: G884-G895, 2010. First published March 25, 2010; doi: 10.
Blomquist, Charles H., Anttila, Chelsea, Mason, J. Ian, Delvoux, Bert, Romano, Andrea; id_orcid, Albrecht, Jeffrey H., Mullany, Lisa K., Hanse, Eric A., Romano, Andrea   +8 more
core   +1 more source

The Difference in the Cyclin D1 Expression in Advanced Stage Nasopharyngeal Cancer based on Treatment Response: A Retrospective Cohort Study

Acta Medica Indonesiana, 2020
Background: nasopharyngeal cancer (NPC) is the most common type of head and neck cancer in Indonesia (28.4%). Reports showed that 18.9% of cases came with advanced stage. Chemotherapy play important role in advanced stage. However, patients with the same
Cosphiadi Irawan, Rahmat Cahyanur, Lisnawati Lisnawati, Murdani Abdullah, Reyhan Eddy Yunus   +4 more
doaj   +2 more sources

Kinase independent oncogenic cyclin D1

Aging, 2015
Strong evidence implicates cyclin D1 overexpression as a driving force in breast cancer and many other types of human tumors. Cyclin D1 overexpression is found in up to 50% of human breast cancers, and the pattern of cyclin D1 overexpression in tissues along the spectrum from normal epithelium to invasive breast cancer suggests its involvement in the ...
Casimiro, Mathew C, Arnold, Andrew, Pestell, Richard   +2 more
openaire   +2 more sources

Expression of cyclin D1 in clear cell sarcoma of kidney. Is it useful in differentiating it from its histological mimics?

Diagnostic Pathology, 2019
Background Clear cell sarcoma of the kidney (CCSK) is a rare malignant pediatric renal neoplasm with a heterogeneous histological appearance which often results in misdiagnosis.
Nasir Uddin, Khurram Minhas, Jamshid Abdul-Ghafar, Arsalan Ahmed, Zubair Ahmad   +4 more
doaj   +1 more source

Brucine Inhibits the Proliferation of Human Lung Cancer Cell Line PC-9 
via Arresting Cell Cycle

Chinese Journal of Lung Cancer, 2014
Background and objective It has been proven that Cyclin D1 and Cyclin E are the important positive regulators of cell cycle, they are closely related to the tumor proliferation. The aim of this study is to explore the relationship between Brucine and the
Miao LI, Ping LI, Mei ZHANG, Feng MA, Li SU   +4 more
doaj   +1 more source

The cyclin D1 gene is transcriptionally repressed by caveolin-1

, 2000
The cyclin D1 gene encodes the regulatory subunit of the holoenzyme that phosphorylates and inactivates the retinoblastoma pRB protein. Cyclin D1 protein levels are elevated by mitogenic and oncogenic signaling pathways, and antisense mRNA to cyclin D1 ...
Bash, Tal, Fu, Maofu, Albanese, Chris, Shtutman, Michael, Ben-Ze'ev, Avri, Hulit, James, Pestell, Richard G., Zhurinsky, Jacob, Lisanti, Michael P., Galbiati, Ferruccio, Sage, Daniel R., Schlegel, Amnon   +11 more
core   +1 more source

CDK-Independent Activation of Estrogen Receptor by Cyclin D1 [PDF]

, 1997
Both cyclin D1 and estrogens have an essential role in regulating proliferation of breast epithelial cells. We show here a novel role for cyclin D1 in growth regulation of estrogen-responsive tissues by potentiating transcription of estrogen receptor ...
Wientjens, Ellen, van der Sman, Jeroen, Michalides, Rob J.A.M, Klompmaker, Rob, Zwijsen, Renate M.L, Bernards, René   +5 more
core   +1 more source

Prognostic significance of cyclin D1 protein expression and gene amplification in invasive breast carcinoma.

PLoS ONE, 2017
The oncogenic capacity of cyclin D1 has long been established in breast cancer. CCND1 amplification has been identified in a subset of patients with poor prognosis, but there are conflicting data regarding the predictive value of cyclin D1 protein ...
Angela B Ortiz, Diego Garcia, Yolanda Vicente, Magda Palka, Carmen Bellas, Paloma Martin   +5 more
doaj   +1 more source

Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study

Biology of Sex Differences, 2011
Background Although colorectal cancer (CRC) is generally not considered to be a hormone-dependent malignancy, several sex-related differences in incidence, molecular characteristics and survival have been reported.
Wangefjord Sakarias, Manjer Jonas, Gaber Alexander, Nodin Björn, Eberhard Jakob, Jirström Karin   +5 more
doaj   +1 more source

New twist in the regulation of cyclin D1

bmc, 2010
Abstract Among the cell cycle-related mammalian cyclins, cyclin D1 is more closely connected with cell proliferation in response to extracellular signals than the cell cycle clock itself. Because both its mRNA and protein are labile, the intracellular abundance of cyclin D1 is thought to be largely regulated at the level of ...
Kato Jun-ya, Yoneda-Kato Noriko
openaire   +3 more sources