Results 101 to 110 of about 299,961 (316)
The Relationships between cyclin D1 Expression and Prognosis of Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer, 2010 Background and objective cyclin D1 is a member of the cyclin family, and it has been proven that it plaied an important role in tumorigenesis, invasion and metastasis.
Jiping ZHU +4 more
doaj
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
The role of anchorage in cell cycle control [PDF]
, 2009 Mammalian cells generally require both mitogens and anchorage signals in order to proliferate. Failure to receive these signals results in either cell-cycle arrest or cell death, known as anoikis, due to activation of anchorage-dependent checkpoint ...
Cremona, C.A.
core
Activation of cyclin D1 expression by the ERK5 cascade [PDF]
, 2003 Transcriptional activation of the cyclin D1 gene is a key step in cell proliferation. Accordingly, cyclin D1 overexpression is frequently an early step in neoplastic transformation, particularly in mammary epithelium.
Hipskind, R. A. +3 more
core +1 more source
Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells
Neural Development, 2009 Background Maintaining the correct balance of proliferation versus differentiation in retinal progenitor cells (RPCs) is essential for proper development of the retina.
Choi Yoon +3 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli +6 more
wiley +1 more source
The Relationship between MACC1/c-Met/Cyclin D1 Axis Expression and Prognosis in ESCC
Analytical Cellular Pathology, 2022 Background. Esophageal cancer is one of the most common malignant tumors of the digestive system, with high incidence and mortality. Methods. Immunohistochemical method was used to detect the expression of MACC1, c-Met, and cyclin D1 in ESCC and its ...
Yan Shi +8 more
doaj +1 more source
OncoTarget, 2015 Ewing sarcoma is an aggressive bone and soft tissue tumor in children and adolescents, with treatment remaining a clinical challenge. This disease is mediated by somatic chromosomal translocations of the EWS gene and a gene encoding an ETS transcription ...
A. Kennedy +11 more
semanticscholar +1 more source
Animal Research and One Health, EarlyView.Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue +10 more
wiley +1 more source
Journal of Translational Medicine, 2015 Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive.
Maria Feldt +8 more
semanticscholar +1 more source