Results 151 to 160 of about 3,126,054 (284)

Focusing on cyclin-dependent kinases 5: A potential target for neurological disorders. [PDF]

Front Mol Neurosci, 2022
Tian Z, Feng B, Wang XQ, Tian J.
europepmc   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

Epilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley, Peter Widdess‐Walsh, Christine Linehan, Danielle M. Andrade, Norman Delanty, Patrick B. Moloney   +5 more
wiley   +1 more source

The Cyclin-dependent Kinase Family

Cold Spring Harbor Symposia on Quantitative Biology, 1991
M, Meyerson, B, Faha, L K, Su, E, Harlow, L H, Tsai   +4 more
openaire   +2 more sources

Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities. [PDF]

J Cancer Res Clin Oncol, 2023
Zabihi M, Lotfi R, Yousefi AM, Bashash D.   +3 more
europepmc   +1 more source

Exploring medical food supplementation as an adjunct strategy for microbiota restoration and seizure reduction in CDKL5 deficiency disorder

Epilepsia Open, EarlyView.
Abstract Objectives CDKL5 deficiency disorder (CDD) is a developmental and epileptic encephalopathy characterized by early‐onset, treatment‐resistant seizures and severe neurodevelopmental impairment. Increasing evidence suggests that alterations in the gut–brain axis may contribute to disease pathophysiology, raising interest in microbiota‐targeted ...
Elisa Borghi, Matteo Domenico Marsiglia, Francesca Triva, Emerenziana Ottaviano, Ilaria Viganò, Miriam Nella Savini, Valentino Costabile, Aglaia Vignoli   +7 more
wiley   +1 more source

The Emerging Role of Transcription-Associated Cyclin-Dependent Kinases in Gastrointestinal Tumors. [PDF]

Cancers (Basel)
Athavale D, Pulipati D, Balch C, Zhao J, Zhang Y, Yao X, Song S.   +6 more
europepmc   +1 more source

Inhibition of Cyclin-Dependent Kinases 8/19 Restricts Bacterial and Virus-Induced Inflammatory Responses in Monocytes. [PDF]

Viruses, 2023
Kokinos EK, Tsymbal SA, Galochkina AV, Bezlepkina SA, Nikolaeva JV, Vershinina SO, Shtro AA, Tatarskiy VV, Shtil AA, Broude EV, Roninson IB, Dukhinova M.   +11 more
europepmc   +1 more source

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Targeting Transcriptional Cyclin-Dependent Kinases in Cancer. [PDF]

Mol Cancer Ther
Kolodziejczyk A, Sicinski P.
europepmc   +1 more source

Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases. [PDF]

Sci Transl Med, 2023
Kartha N, Gianopulos JE, Schrank Z, Cavender SM, Dobersch S, Kynnap BD, Wallace-Povirk A, Wladyka CL, Santana JF, Kim JC, Yu A, Bridgwater CM, Fuchs K, Dysinger S, Lampano AE, Notta F, Price DH, Hsieh AC, Hingorani SR, Kugel S.   +19 more
europepmc   +1 more source