Cyclin-Dependent Kinases 4 and 6 Inhibitors: An Emerging Therapeutic Framework from Growth Suppression to Tumor Clearance. [PDF]
Ma C +7 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Transcriptional cyclin-dependent kinases Cdk8 and Cdk19 are required for normal macrophage differentiation. [PDF]
Kolodziejczyk A +12 more
europepmc +1 more source
Transcription associated cyclin-dependent kinases as therapeutic targets for prostate cancer. [PDF]
Constantin TA +3 more
europepmc +1 more source
Cyclins and cyclin-dependent kinases: a biochemical view [PDF]
openaire +2 more sources
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea +4 more
wiley +1 more source
When cyclin-dependent kinases meet viral infections, including SARS-CoV-2. [PDF]
Yan Y, Tang YD, Zheng C.
europepmc +1 more source
ABSTRACT Dedifferentiated liposarcoma (DDLPS) is a rare soft tissue sarcoma with limited real‐world epidemiologic data. This nationwide retrospective study describes the epidemiology, management, and outcomes of DDLPS in France using the NETSARC+ national sarcoma registry.
Julien Bollard +23 more
wiley +1 more source
Mechanistic Roles of Transcriptional Cyclin-Dependent Kinases in Oncogenesis: Implications for Cancer Therapy. [PDF]
Alrouji M +4 more
europepmc +1 more source
Comprehensive Analysis of Role of Cyclin-Dependent Kinases Family Members in Colorectal Cancer. [PDF]
Guan L, Tang Y, Li G, Qin Z, Li S.
europepmc +1 more source

