Results 1 to 10 of about 3,707,282 (391)

A study towards the synthesis of (-)-atrop-abyssomicin C core [PDF]

Journal of the Serbian Chemical Society, 2021
An attempt to synthesize the cyclohexane core of antibiotic abyssomicin C is described. The initial, protecting group-free approach (relying on internal protection) failed and had to be modified, in order to allow for efficient deprotection of the acid ...
Saičić Radomir N., Trmčić Milena
doaj   +1 more source

Cyclization mechanism and kinetics of poly(acrylonitrile-co-2-acrylamido-2-methylpropane sulfonic acid) copolymer investigated by FTIR spectroscopy

Polymer Testing, 2021
Cyclization reaction of poly(acrylonitrile-co-2-acrylamido-2-methylpropane sulfonic acid) [P(AN-co-AMPS)] copolymer during thermal oxidative stabilization (TOS) process was investigated by FTIR and two dimensional (2D) correlation analysis technique. The
Zhipeng He, Huichao Liu, Guang Yang, Chi Jiang, Muwei Ji, Jiali Yu, Mingliang Wang, Caizhen Zhu, Jian Xu   +8 more
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Applications of transition state calculations in the key cyclization of small molecule natural product synthesis [PDF]

E3S Web of Conferences, 2021
The diversification of the conformation and configuration of the carbocyclic skeleton of natural products is an important reason for the diversity and complexity of the structure of natural products.
Qiu Rongxiang
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Harnessing the cyclization strategy for new drug discovery

Acta Pharmaceutica Sinica B, 2022
The design of new ligands with high affinity and specificity against the targets of interest has been a central focus in drug discovery. As one of the most commonly used methods in drug discovery, the cyclization represents a feasible strategy to ...
Kai Tang, Shu Wang, Wenshuo Gao, Yihui Song, Bin Yu   +4 more
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6-Endo-dig cyclization: Flexible enforce to develop synthetic route in organic syntheses

Results in Chemistry, 2023
The organic ring closure reaction of diverse acyclic compounds is governed mostly by the Baldwin rule. The ring closure compounds shows emergent application.
Vembu Yogeshwaran, Senthilkumar Dhayanithi, Periasamy Vinoth Kumar, Selvaraj Mohana Roopan   +3 more
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Influence of Monomer Sequence on the Cyclization Behavior of Poly(acrylonitrile-co-acrylamide)

Applied Sciences, 2023
In this research, we have developed the approach to controlled synthesis of acrylonitrile-acrylamide copolymers with narrow molecular weight distribution and various monomer sequence distributions.
Roman V. Toms, Mikhail S. Balashov, Alexander Yu. Gervald, Nikolay I. Prokopov, Anna V. Plutalova, Elena V. Chernikova   +5 more
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Efficient Synthesis of Isoquinoline Derivatives through Sequential Cyclization–Deoxygenation Reaction of 2-Alkynylbenzaldoximes

SynOpen, 2022
We describe a novel, simple, robust, and efficient cyclization/deoxygenation approach for the synthesis of functionalized isoquinoline derivatives. Over the course of continued studies on o-alkynylbenzaldoxime cyclization reactions, the formation of ...
Mojtaba Ayoubi, Ali Nikbakht, Kamran Amiri, Alireza Abbasi Kejani, Hossein Zahedian Tejeneki, Saeed Balalaie   +5 more
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Cannabidiol as the Substrate in Acid-Catalyzed Intramolecular Cyclization

Journal of Natural Products, 2020
The chemical reactivity of cannabidiol is based on its ability to undergo intramolecular cyclization driven by the addition of a phenolic group to one of its two double bonds.
Paola Marzullo, Francesca Foschi, David Coppini, Fabiola Fanchini, L. Magnani, S. Rusconi, M. Luzzani, D. Passarella   +7 more
semanticscholar   +1 more source

Unified short syntheses of oxygenated tricyclic aromatic diterpenes by radical cyclization with a photoredox catalyst

Communications Chemistry, 2023
The biomimetic two-phase strategy employing polyene cyclization and subsequent oxidation/substitution is an effective approach for divergent syntheses of [6-6-6]-tricyclic diterpenes.
Riichi Hashimoto, Kengo Hanaya, Takeshi Sugai, Shuhei Higashibayashi   +3 more
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Oxidative Cyclization at ortho-Position of Phenol: Improved Total Synthesis of 3-(Phenethylamino)demethyl(oxy)aaptamine

Marine Drugs, 2023
A shorter synthesis of the demethyl(oxy)aaptamine skeleton was developed via oxidative intramolecular cyclization of 1-(2-azidoethyl)-6-methoxyisoquinolin-7-ol followed by dehydrogenation with a hypervalent iodine reagent.
Yuki Nakatani, Risa Kimura, Tomoyo Kimata, Naoyuki Kotoku   +3 more
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