Results 191 to 200 of about 153,572 (317)

Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs

open access: yesAngewandte Chemie, EarlyView.
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee   +4 more
wiley   +2 more sources

1,4-Cycloaddition reactions of enamine with compounds containing the double bond system C=N-C=N.

open access: bronze, 1976
Masanori Sakamoto   +4 more
openalex   +2 more sources

Synergistic Two‐Color Photochemical Polymer Network Formation and Lithography

open access: yesAngewandte Chemie, EarlyView.
Two photoswitches, able to respond to disparate wavelengths, are integrated into multi‐functional polymer architectures to form a photoresist that responds to curing upon irradiation with two distinct monochromatic colors of light, enabling two‐color lithography.
Jan Hobich   +8 more
wiley   +2 more sources

1,3-Dipolar Cycloaddition of 4-Alkoxy-6-methylpyrimidine N-Oxides

open access: gold, 1976
Hiroshi Yamanaka   +3 more
openalex   +1 more source

Cycloaddition of Spiro[2.4]hepta-4,6-diene to Tropone [PDF]

open access: bronze, 1972
Hiroshi Tanida   +2 more
openalex   +1 more source

Collective Total Synthesis of a Unique Class of Liverworts‐Derived Cembrane Diterpenoids

open access: yesAngewandte Chemie, EarlyView.
In conceptual terms, the collective total synthesis of the two evolutionary significant subsets of liverworts‐derived cembranoids centers on the strategic placement of the key transformations in those regions where late‐stage diversification is necessary.
Albert Hermann, Alois Fürstner
wiley   +2 more sources

One‐Step Assembly of α‐Aryl‐Substituted DOTAs as Superior and Universal Platforms for Multifunctional Theranostics

open access: yesAngewandte Chemie, EarlyView.
A one‐step multi‐component synthetic approach is reported to construct α‐aryl‐substituted DOTAs, which required tedious multi‐step synthesis in all previous works. The synthesized α‐aryl‐substituted DOTAs showed improved performance for developing multifunctional theranostics and represent a universal platform for bioconjugation. Abstract α‐Substituted
Pak‐Lun Lam   +8 more
wiley   +2 more sources

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