Results 31 to 40 of about 3,998 (209)

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

r-1,t-3-Bis[4-(dimethylamino)phenyl]-c-2,t-4-bis(pyridin-4-yl)cyclobutane

open access: yesActa Crystallographica Section E, 2014
The title compound, C30H32N4, was synthesized by the photodimerization of trans-4-{2-[4-(dimethylamino)phenyl]ethenyl}pyridine in benzene upon irradiation with UV light.
Shuguang Zhang, Junpeng Zhuang
doaj   +1 more source

Synthesis of Cyclobutane Serine Analogues

open access: yesThe Journal of Organic Chemistry, 2004
In this paper, we describe a thermal [2 + 2] cycloaddition involving 2-acylaminoacrylates as electron-poor acceptor alkenes, a reaction that involves a Michael-Dieckmann-type process. The reaction gives rise to a new substituted cyclobutane skeleton that can be transformed into amino acid derivatives.
Avenoza, A.   +3 more
openaire   +4 more sources

Anethole Isomerization and Dimerization Induced by Acid Sites or UV Irradiation

open access: yesMolecules, 2010
The formation of cis-anethole and various dimers as a result of the exposure of trans-anethole to microporous solid acids (dealuminated HY zeolites), or UV-Vis irradiation was established by means of high resolution gas chromatography coupled to mass ...
Elena Stashenko   +2 more
doaj   +1 more source

Regiodivergent photocyclization of dearomatized acylphloroglucinols: asymmetric syntheses of (—)-nemorosone and (—)-6-epi-garcimultiflorone A [PDF]

open access: yes, 2019
Regiodivergent photocyclization of dearomatized acylphloroglucinol substrates has been developed to produce type A polycyclic polyprenylated acylphloroglucinol (PPAP) derivatives using an excited-state intramolecular proton transfer (ESIPT) process ...
Boyce, Jonathan H.   +4 more
core   +1 more source

[2+2]-Photocycloadditions of 1,4-Naphthoquinone Under Batch and Continuous-Flow Conditions

open access: yesMolecules
A series of [2+2]-photocycloadditions of 1,4-naphthoquinone with various alkenes and diphenylacetylene were investigated under batch and continuous-flow conditions.
Madyan A. Yaseen   +3 more
doaj   +1 more source

Reversible photoswitching of the DNA-binding properties of styrylquinolizinium derivatives through photochromic [2 + 2] cycloaddition and cycloreversion

open access: yesBeilstein Journal of Organic Chemistry, 2020
It was demonstrated that styrylquinolizinium derivatives may be applied as photoswitchable DNA ligands. At lower ligand:DNA ratios (≤1.5), these compounds bind to duplex DNA by intercalation, with binding constants ranging from Kb = 4.1 × 104 M to 2.6 ...
Sarah Kölsch   +4 more
doaj   +1 more source

UV-Induced Structural Changes of Model DNA Helices Probed by Optical Spectroscopy [PDF]

open access: yes, 2009
International audienceChemical alterations of DNA, if not repaired, may lead to carcinogenic mutations. Structural modifications of the helix around the lesion enable its recognition by repair enzymes.
Bányász, A.   +4 more
core   +4 more sources

Phytochemical Constituents of Combretum Loefl. (Combretaceae) [PDF]

open access: yes, 2013
Combretum is the largest and most widespread genus of Combretaceae. The genus comprises approximately 250 species distributed throughout the tropical regions mainly in Africa and Asia.
Dawe, Amadou   +3 more
core   +1 more source

Using Long‐Chain Polymechanophores to Explore the Differences in Mechanoactivation During Nozzle Flow and Ultrasonication

open access: yesAdvanced Functional Materials, EarlyView.
Flow through a nozzle is a common component of most fluid‐based polymer processing techniques such as spray drying, inkjet printing, extrusion. An ultrahigh molecular weight multi‐mechanophore system is used to probe the differences in the distribution of mechanical activation observed between nozzle flow and ultrasonication; the gold standard ...
Niamh Willis‐Fox   +4 more
wiley   +1 more source

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