Results 71 to 80 of about 577 (161)

Production of Destruxins by Coprotrophic Beauveria feline No. 7 Strain

Антибиотики и Химиотерапия, 2020
Beauveria feline No. 7 strain was isolated from the shrewmouse wool and characterized by production of a complex of destruxins cyclodepsipeptides. The strain was shown to produce significant quatities of destruxin B and pseudodestruxin C.
M. V. Bibikova, T. O. Puzhevskaya, A. N. Danilenko, I. A. Spiridonova, G. V. Zatonsky, A. V. Aleksandrova, A. V. Katlinsky   +6 more
doaj  

Influence of regional and yearly weather patterns on multi‐mycotoxin occurrence in Austrian wheat: a liquid chromatographic–tandem mass spectrometric and multivariate statistics approach

Journal of the Science of Food and Agriculture, Volume 104, Issue 13, Page 7788-7796, October 2024.
Abstract BACKGROUND Mycotoxin surveys play an essential role in our food safety system. The obtained occurrence data form the basis for the assessment of the exposure of humans and animals to these toxic fungal secondary metabolites. Liquid chromatography coupled with tandem mass spectrometry (LC‐MS/MS) has become the gold standard for mycotoxin ...
Stephan Freitag, Michael Sulyok, Elisabeth Reiter, Maximilian Lippl, Klemens Mechtler, Rudolf Krska   +5 more
wiley   +1 more source

Inhibition of Virulence Gene Expression in Staphylococcus aureus by Novel Depsipeptides from a Marine Photobacterium

Marine Drugs, 2011
During a global research expedition, more than five hundred marine bacterial strains capable of inhibiting the growth of pathogenic bacteria were collected.
Lone Gram, Hanne Ingmer, Louise Kjærulff, Charlotte H. Gotfredsen, Matthias Wietz, Anita Nielsen, Thomas O. Larsen, Maria Mansson   +7 more
doaj   +1 more source

Re‐Engineering Fungal Nonribosomal Peptide Synthetases by Module Dissection and Duplicated Thiolation Domains

Angewandte Chemie, Volume 136, Issue 33, August 12, 2024.
A new strategy is presented to dissect fungal nonribosomal peptide synthetases into “splitting unit” pairs (SUPs). Collaboration in SUPs is facilitated by artificial duplication of the thiolation domain and its linkers, and an optimized split site. The productivities of SUPs match or exceed those of the corresponding single‐subunit chimeras or even ...
Miaomiao Yin, Linan Xie, Kang Chen, Liwen Zhang, Qun Yue, Chen Wang, Juntian Zeng, Xiaoyang Hao, Xiaofeng Gu, István Molnár, Yuquan Xu   +10 more
wiley   +1 more source

Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides

Fungal Biology and Biotechnology, 2018
Background Fungal cyclodepsipeptides (CDPs) are non-ribosomally synthesized peptides produced by a variety of filamentous fungi and are of interest to the pharmaceutical industry due to their anticancer, antimicrobial and anthelmintic bioactivities ...
Simon Boecker, Stefan Grätz, Dennis Kerwat, Lutz Adam, David Schirmer, Lennart Richter, Tabea Schütze, Daniel Petras, Roderich D. Süssmuth, Vera Meyer   +9 more
doaj   +1 more source

Comparative Structure–Activity Analysis of the Antimicrobial Activity, Cytotoxicity, and Mechanism of Action of the Fungal Cyclohexadepsipeptides Enniatins and Beauvericin

Toxins, 2019
Filamentous fungi, although producing noxious molecules such as mycotoxins, have been used to produce numerous drugs active against human diseases such as paclitaxel, statins, and penicillin, saving millions of human lives.
Hamza Olleik, Cendrine Nicoletti, Mickael Lafond, Elise Courvoisier-Dezord, Peiwen Xue, Akram Hijazi, Elias Baydoun, Josette Perrier, Marc Maresca   +8 more
doaj   +1 more source

Pigmentosins from Gibellula sp. as antibiofilm agents and a new glycosylated asperfuran from Cordyceps javanica

Beilstein Journal of Organic Chemistry, 2019
In the course of our exploration of the Thai invertebrate-pathogenic fungi for biologically active metabolites, pigmentosin A (1) and a new bis(naphtho-α-pyrone) derivative, pigmentosin B (2), were isolated from the spider-associated fungus Gibellula sp.
Soleiman E. Helaly, Wilawan Kuephadungphan, Patima Phainuphong, Mahmoud A. A. Ibrahim, Kanoksri Tasanathai, Suchada Mongkolsamrit, Janet Jennifer Luangsa-ard, Souwalak Phongpaichit, Vatcharin Rukachaisirikul, Marc Stadler   +9 more
doaj   +1 more source

Synthesis of the polyketide section of seragamide A and related cyclodepsipeptides via Negishi cross coupling

Beilstein Journal of Organic Chemistry, 2019
The synthesis of the polyketide section present in the potently cytotoxic marine cyclodepsipeptide jasplakinolide and related natural products, geodiamolides and seragamides, is reported.
Jan Hendrik Lang, Thomas Lindel
doaj   +1 more source

Marine Organisms as a Prolific Source of Bioactive Depsipeptides. [PDF]

Mar Drugs, 2023
Zeng M, Tao J, Xu S, Bai X, Zhang H.
europepmc   +1 more source

Chemometrics and genome mining reveal an unprecedented family of sugar acid-containing fungal nonribosomal cyclodepsipeptides. [PDF]

Proc Natl Acad Sci U S A, 2022
Wang C, Xiao D, Dun B, Yin M, Tsega AS, Xie L, Li W, Yue Q, Wang S, Gao H, Lin M, Zhang L, Molnár I, Xu Y.   +13 more
europepmc   +1 more source