Results 131 to 140 of about 85,052 (307)

Controlled Delivery and Light‐Induced Release of Magic Spot Nucleotides in Escherichia coli

open access: yesAngewandte Chemie International Edition, EarlyView.
We synthesized photocaged, clickable and isotope‐labeled “magic spot” Nucleotides and delivered them into Escherichia coli comparing different approaches. Light‐controlled release inside living cells enabled tracking of their conversion from pppGpp to ppGpp by capillary electrophoresis mass spectrometry and revealed their impact on the growth rate of a
Christoph Popp   +12 more
wiley   +1 more source

Inclusion complex of amiodarone hydrochloride with cyclodextrins: preparation, characterization and dissolution rate evaluation

open access: green, 2022
Alexandre Machado Rubim   +4 more
openalex   +1 more source

o‐Terphenyl‐Based Family of Conjugated Macrocycles: Selective Recognition of Phenylalanine in Water and Interaction With Insulin

open access: yesAngewandte Chemie International Edition, EarlyView.
This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule   +5 more
wiley   +1 more source

Investigation on Cyclodextrin Production with Cyclodextrin Glucanotransferase from Bacillus megaterium

open access: yesFood Technology and Biotechnology, 2008
The process of producing cyclodextrins from starch with cyclodextrin glucanotransferase from Bacillus megaterium has been studied. The effect of starch and enzyme concentrations was evaluated using optimal composite designs and the response surface ...
Ivan Genov Pishtiyski   +2 more
doaj  

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

Hidden O‐Deglycosylation Activity Triggers O → C Rearrangement for Aryl Di‐C‐Glucoside Formation by the C‐Glycosyltransferase From Fortunella crassifolia

open access: yesBiotechnology and Bioengineering, EarlyView.
Here, we uncovered an unexpected O‐deglycosylation activity of the C glycosyltransferase (FcCGT), forming phloretin (1) from phloretin 2'‐O‐glucoside (2). In the presence of UDP, FcCGT catalyzes the O→C rearrangement to yield nothofagin (3). Upon additional UDP‐glucose, further C‐glycosylation occurs, forming phloretin 3',5'‐di‐C‐glucoside (4 ...
Tuo Li   +4 more
wiley   +1 more source

Cationic Cyclodextrin-Based Carriers for Drug and Nucleic Acid Delivery

open access: yesPharmaceutics
Cyclodextrins can serve as carriers for various payloads, utilizing their capacity to form unique host–guest inclusion complexes within their cavity and their versatile surface functionalization.
Adila Nazli   +3 more
doaj   +1 more source

CHARACTERIZATION OF RUTIN-CYCLODEXTRIN INCLUSION COMPOUNDS [PDF]

open access: yes, 2011
The objectives of this study were to examine the potential of beta-cyclodextrin to improve the solubility of rutin and obtain inclusion compounds that were analyzed by different techniques: UV-Vis, IR spectroscopy, thermal analysis.
Andreia Corciovă, Dan Caşcaval
core  

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