Results 1 to 10 of about 22,053,927 (171)
Upregulation of prostaglandin E by inducible microsomal prostaglandin E synthase-1 in colon cancer [PDF]
Purpose Prostaglandin E2 (PGE2) is known to promote carcinogenesis and cancer progression in colon cancer. Enzymes involved in the metabolism of PGE2 include cyclooxygenase (COX)-2, microsomal prostaglandin E synthase-1 (mPGES-1), and 15-prostaglandin ...
Young Hun Kim, Kyung Jong Kim
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Prostaglandin Synthase 2/Cyclooxygenase 2 Gene Polymorphisms and Susceptibility to Urothelial Bladder Cancer in an Iranian Population [PDF]
Background: Prostaglandin-endoperoxide synthase 2, recognized as cyclooxygenase 2 (COX-2), is an important enzyme contributing to the generation of proinflammatory prostaglandins.
Kamyar Mansori+3 more
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Endometritis in the bitch: Immunohistochemical localization of cyclooxygenase 2 [PDF]
Background: In several mammals, subfertility or infertility associated with endometritis was reported. Although there have been studies about endometritis in bitches, the pathophysiological mechanisms it is not completely known. Aim: This study aimed to
María Carla García Mitacek+4 more
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Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer.
Christoph F. A. Vogel+16 more
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Correlation of COX- 2 Expression in Colorectal Carcinoma with Clinicopathological Features [PDF]
Objective: Colorectal carcinoma is the most common neoplasm of the gastrointestinal tract. COX-2 expression is upregulated in colorectal carcinoma. Therefore its assessment would identify patients amenable to adjuvant anticyclooxygenase therapy.
Sandhya VENKATACHALA, Manjula RAJENDRAN
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The Role of Cyclooxygenase-2 in Colorectal Cancer
Colorectal cancer is the third common cancer in this world, accounting for more than 1 million cases each year. However, detailed etiology and mechanism of colorectal cancer have not been fully understood.
Juan Sheng+5 more
semanticscholar +1 more source
Genetic Variants in COX2 and ALOX Genes and Breast Cancer Risk in White and Black Women
COX and ALOX genes are involved in inflammatory processes and that may be related to breast cancer risk differentially between White and Black women. We evaluated distributions of genetic variants involved in COX2 and ALOX-related pathways and examined ...
Jennifer M. Mongiovi+10 more
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Background Pituitary adenomas as multifactorial intracranial neoplasms impose a massive burden of morbidity on patients and characterizing the molecular mechanism underlying their pathogenesis has received considerable attention.
Nasrin Akbari+9 more
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The roots of Astilbe grandis, known as “Ma sang gou bang”, are used as a Miao traditional medicine with anti-inflammatory and analgesic properties. However, the active components and mechanism of action of this plant remain mostly uncharacterized.
Jin-Fang Luo+6 more
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Electrospraying (ES) technology is considered an efficient micro/nanoparticle fabrication technique with controlled dimensions and diverse morphology.
Samar Zuhair Alshawwa+5 more
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