Results 1 to 10 of about 22,053,927 (171)

Upregulation of prostaglandin E by inducible microsomal prostaglandin E synthase-1 in colon cancer [PDF]

open access: yesAnnals of Coloproctology, 2022
Purpose Prostaglandin E2 (PGE2) is known to promote carcinogenesis and cancer progression in colon cancer. Enzymes involved in the metabolism of PGE2 include cyclooxygenase (COX)-2, microsomal prostaglandin E synthase-1 (mPGES-1), and 15-prostaglandin ...
Young Hun Kim, Kyung Jong Kim
doaj   +1 more source

Prostaglandin Synthase 2/Cyclooxygenase 2 Gene Polymorphisms and Susceptibility to Urothelial Bladder Cancer in an Iranian Population [PDF]

open access: yesMiddle East Journal of Cancer, 2022
Background: Prostaglandin-endoperoxide synthase 2, recognized as cyclooxygenase 2 (COX-2), is an important enzyme contributing to the generation of proinflammatory prostaglandins.
Kamyar Mansori   +3 more
doaj   +1 more source

Endometritis in the bitch: Immunohistochemical localization of cyclooxygenase 2 [PDF]

open access: yesOpen Veterinary Journal, 2020
Background: In several mammals, subfertility or infertility associated with endometritis was reported. Although there have been studies about endometritis in bitches, the pathophysiological mechanisms it is not completely known. Aim: This study aimed to
María Carla García Mitacek   +4 more
doaj   +1 more source

Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development

open access: yesFrontiers in Immunology, 2021
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer.
Christoph F. A. Vogel   +16 more
doaj   +1 more source

Correlation of COX- 2 Expression in Colorectal Carcinoma with Clinicopathological Features [PDF]

open access: yesTürk Patoloji Dergisi, 2017
Objective: Colorectal carcinoma is the most common neoplasm of the gastrointestinal tract. COX-2 expression is upregulated in colorectal carcinoma. Therefore its assessment would identify patients amenable to adjuvant anticyclooxygenase therapy.
Sandhya VENKATACHALA, Manjula RAJENDRAN
doaj   +1 more source

The Role of Cyclooxygenase-2 in Colorectal Cancer

open access: yesInternational Journal of Medical Sciences, 2020
Colorectal cancer is the third common cancer in this world, accounting for more than 1 million cases each year. However, detailed etiology and mechanism of colorectal cancer have not been fully understood.
Juan Sheng   +5 more
semanticscholar   +1 more source

Genetic Variants in COX2 and ALOX Genes and Breast Cancer Risk in White and Black Women

open access: yesFrontiers in Oncology, 2021
COX and ALOX genes are involved in inflammatory processes and that may be related to breast cancer risk differentially between White and Black women. We evaluated distributions of genetic variants involved in COX2 and ALOX-related pathways and examined ...
Jennifer M. Mongiovi   +10 more
doaj   +1 more source

Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas

open access: yesBMC Endocrine Disorders, 2020
Background Pituitary adenomas as multifactorial intracranial neoplasms impose a massive burden of morbidity on patients and characterizing the molecular mechanism underlying their pathogenesis has received considerable attention.
Nasrin Akbari   +9 more
doaj   +1 more source

Triterpenoid and Coumarin Isolated from Astilbe grandis with Anti-Inflammatory Effects through Inhibiting the NF-κB Pathway in LPS-Induced RAW264.7 Cells

open access: yesMolecules, 2023
The roots of Astilbe grandis, known as “Ma sang gou bang”, are used as a Miao traditional medicine with anti-inflammatory and analgesic properties. However, the active components and mechanism of action of this plant remain mostly uncharacterized.
Jin-Fang Luo   +6 more
doaj   +1 more source

Fabrication of Celecoxib PVP Microparticles Stabilized by Gelucire 48/16 via Electrospraying for Enhanced Anti-Inflammatory Action

open access: yesPharmaceuticals, 2023
Electrospraying (ES) technology is considered an efficient micro/nanoparticle fabrication technique with controlled dimensions and diverse morphology.
Samar Zuhair Alshawwa   +5 more
doaj   +1 more source

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