Results 121 to 130 of about 31,607 (207)

The control of viral infection by tripartite motif proteins and cyclophilin A

Retrovirology, 2007
The control of retroviral infection by antiviral factors referred to as restriction factors has become an exciting area in infectious disease research.
Towers Greg J
doaj   +1 more source

Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway. [PDF]

Int J Mol Med, 2023
Yoon JS, Kim SS, Ha J, Kang I, Choe W.
europepmc   +1 more source

Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes

BMC Immunology, 2010
Background Gene expression in lipopolysaccharide (LPS)-stimulated monocytes is mainly studied by quantitative real-time reverse transcription PCR (RT-qPCR) using GAPDH (glyceraldehyde 3-phosphate dehydrogenase) or ACTB (beta-actin) as reference gene for ...
Øvstebø Reidun, Grimholt Runa M, Piehler Armin P, Berg Jens P   +3 more
doaj   +1 more source

Human Cyclophilin B Nuclease Activity Revealed via Nucleic Acid-Based Electrochemical Sensors. [PDF]

Angew Chem Int Ed Engl, 2022
Clark V, Waters K, Orsburn B, Bumpus NN, Kundu N, Sczepanski JT, Ray P, Arroyo-Currás N.   +7 more
europepmc   +1 more source

Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules.

, 2015
Human cytomegalovirus uses a variety of mechanisms to evade immune recognition through major histocompatibility complex class I molecules. One mechanism mediated by the immunoevasin protein US2 causes rapid disposal of newly synthesized class I molecules
Daniel C. Chapman (839142), Pawel Stocki (839143), Daniel C Chapman, David B. Williams (839144), Pawel Stocki, David B Williams   +5 more
core   +1 more source

Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation [PDF]

, 2019
Peptidyl-prolyl cis/trans isomerases (PPIs) catalyze cis/trans isomerization of peptide bonds preceding proline residues. The involvement of PPI family members in protein refolding has been established in test tube experiments.
Bernasconi, Riccardo, Galli, Carmela, Luban, Jeremy, Soldà, Tatiana, Pertel, Thomas, Molinari, Maurizio   +5 more
core  

ЦИКЛОФИЛИН А: СТРОЕНИЕ И ФУНКЦИИ

, 2017
Cyclophilins belong to a large family of ancient conservative proteins with peptidyl-prolyl-cis-trans isomerase activity. The main member of this family – cyclophilin A – was discovered as an intracellular ligand for cyclosporine A.
D. B. Kazansky, Л. М. Хромых, А. А. Калинина, Д. Б. Казанский, A. A. Kalinina, L. M. Khromykh   +5 more
core   +2 more sources

Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish

, 2011
Tripartite motif proteins (TRIM) constitute a large family of proteins containing a RING-Bbox-Coiled Coil motif followed by different C-terminal domains. Involved in ubiquitination, TRIM proteins participate in many cellular processes including antiviral
Pierre Pontarotti, Pnontarotti, P., Lieke M van der Aa, van der Aa Lieke M., Benmansour, Abdenour, Abdenour Benmansour, Jouneau Luc, Benmansour, A., Pontarotti Pierre, Boudinot Pierre, Van Der Aa, Lieke M, Levraud, Jean-Pierre, Birolat, V., Levraud, L. P., Boudinot, Pierre, Du Pasquier Louis, Jouneau, Luc, Louis Du Pasquier, Benmansour Abdenour, Valérie Briolat, Jean-Pierre Levraud, Pasquier, L., du, Briolat Valérie, Aa, L.M., van der, Pontarotti, P., du Pasquier, L., Van der aa, Lieke, Jouneau, L., Levraud, J.P., Pontarotti, Pierre, van der Aa, L.M., Du Pasquier, Louis, Boudinot, P., Briolat, Valérie, Luc Jouneau, Lieke M. van der Aa, Levraud Jean-Pierre, Boudinot, R., Pierre Boudinot, van der Aa, L. M.   +39 more
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Crystal structure of cyclophilin from Leishmania donovani at 3.5 Å resolution

, 2004
The crystal structure of cyclophilin from Leishmania donovani has been solved at 3.5 Å resolution. The protein with peptidylprolyl cis-trans isomerase activity is also a receptor for the drug, cyclosporin. The crystal structure of cyclophilin obtained in
Dutta, Madhuri, Sen, Malabika, Banerjee, Rahul, Datta, Alok K.   +3 more
core   +1 more source

Time-Resolved Metabolomics Reveals Mitochondrial Protection in Septic Liver Injury

Metabolites
Background/Objectives: Sepsis is a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection. Mitochondrial dysfunction is considered a key contributor to the pathogenesis of sepsis, but its molecular ...
Naoki Suzuki, Shoichiro Shibata, Masahiro Sugimoto, Eskil Elmer, Hiroyuki Uchino   +4 more
doaj   +1 more source