Results 131 to 140 of about 31,607 (207)

The cyclophilin inhibitor alisporivir prevents hepatitis C virus-mediated mitochondrial dysfunction

open access: yes, 2012
Alisporivir (Debio-025) is an analogue of cyclosporine A and represents the prototype of a new class of non-immunosuppressive cyclophilin inhibitors. In vitro and in vivo studies have shown that alisporivir inhibits hepatitis C virus (HCV) replication ...
Vuagniaux, G.   +20 more
core   +1 more source

The Characterization of a Cyclophilin-Type Peptidyl-Prolyl CIS-Trans-Isomerase from the Endoplassimc-Retticulum Lumen

open access: yes, 1994
A luminally located peptidyl prolyl cis-trans-isomerase (PPI) has been purified from bovine liver microsomes. It has a molecular mass of 20.6kDa, and N-terminal sequencing demonstrates strong sequence similarity to the sequences of the cyclophilin B ...
Freedman, Robert B., Mucke, M., Bose, S.
core  

The construction of cyclophilin-binding loop substitutions in the HIV-1 capsid.

open access: yes, 2018
A) (top) Crystal structures of hexameric (pdb:3GV2) and monomeric (pdb:1AK4) HIV-1 capsid. The region shown in red is the cyclophilin-binding loop. (middle) Location of the cyclophilin-binding loop within gag-pol.
Cody J. Warren (563898)   +4 more
core   +1 more source

The control of viral infection by tripartite motif proteins and cyclophilin A-3

open access: yes, 2011
Copyright information:Taken from "The control of viral infection by tripartite motif proteins and cyclophilin A"http://www.retrovirology.com/content/4/1/40Retrovirology 2007;4():40-40.Published online 12 Jun 2007PMCID:PMC1906832.
Greg J Towers (76311)
core   +1 more source

Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor?

open access: yes, 2009
Linard D, Kandlbinder A, Degand H, Morsomme P, Dietz K-J, Knoops B. Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor? ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2009;491(1-2):39-45.Mitochondria are
Dietz, Karl-Josef   +5 more
core   +1 more source

The Cyclophilin A-CD147 complex promotes bone marrow colonization of B-cell malignancies: implications for therapy

open access: yes, 2016
B-cell malignancies frequently colonizes the bone marrow (BM). The mechanisms responsible for this preferential homing are not entirely known. Using multiple myeloma (MM) as a model of a terminally differentiated B-cell malignancy that selectively ...
Munshi, Nikhil   +22 more
core   +1 more source

Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani

open access: yes, 2002
Cyclophilin from the parasite Leishmania donovani is a protein with peptidylprolyl cis±trans isomerase activity, in addition to being a receptor for the drug cyclosporin.
Dutta, Madhuri   +7 more
core   +1 more source

The activity of amyloid beta binding alcohol dehydrogenase in Alzheimer's disease

open access: yes, 2012
The mitochondria are a vibrant hub for many problems that occur in Alzheimer’s disease. The enzyme amyloid-ß binding alcohol dehydrogenase (ABAD) and Cyclophilin D (CypD) are two key mitochondrial proteins that have essential functions in Alzheimer’s ...
Allen, Zoe Eleanor
core  

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