Results 131 to 140 of about 31,607 (207)
The cyclophilin inhibitor alisporivir prevents hepatitis C virus-mediated mitochondrial dysfunction
Alisporivir (Debio-025) is an analogue of cyclosporine A and represents the prototype of a new class of non-immunosuppressive cyclophilin inhibitors. In vitro and in vivo studies have shown that alisporivir inhibits hepatitis C virus (HCV) replication ...
Vuagniaux, G. +20 more
core +1 more source
A luminally located peptidyl prolyl cis-trans-isomerase (PPI) has been purified from bovine liver microsomes. It has a molecular mass of 20.6kDa, and N-terminal sequencing demonstrates strong sequence similarity to the sequences of the cyclophilin B ...
Freedman, Robert B., Mucke, M., Bose, S.
core
The construction of cyclophilin-binding loop substitutions in the HIV-1 capsid.
A) (top) Crystal structures of hexameric (pdb:3GV2) and monomeric (pdb:1AK4) HIV-1 capsid. The region shown in red is the cyclophilin-binding loop. (middle) Location of the cyclophilin-binding loop within gag-pol.
Cody J. Warren (563898) +4 more
core +1 more source
The control of viral infection by tripartite motif proteins and cyclophilin A-3
Copyright information:Taken from "The control of viral infection by tripartite motif proteins and cyclophilin A"http://www.retrovirology.com/content/4/1/40Retrovirology 2007;4():40-40.Published online 12 Jun 2007PMCID:PMC1906832.
Greg J Towers (76311)
core +1 more source
Linard D, Kandlbinder A, Degand H, Morsomme P, Dietz K-J, Knoops B. Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor? ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2009;491(1-2):39-45.Mitochondria are
Dietz, Karl-Josef +5 more
core +1 more source
B-cell malignancies frequently colonizes the bone marrow (BM). The mechanisms responsible for this preferential homing are not entirely known. Using multiple myeloma (MM) as a model of a terminally differentiated B-cell malignancy that selectively ...
Munshi, Nikhil +22 more
core +1 more source
Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani
Cyclophilin from the parasite Leishmania donovani is a protein with peptidylprolyl cis±trans isomerase activity, in addition to being a receptor for the drug cyclosporin.
Dutta, Madhuri +7 more
core +1 more source
Cyclophilin B overexpression predicts a poor prognosis and activates metastatic pathways in colon cancer. [PDF]
Zhang X, Tan J, Yang L, An G.
europepmc +1 more source
Inorganic polyphosphate controls cyclophilin B-mediated collagen folding in osteoblast-like cells. [PDF]
Khong ML +4 more
europepmc +1 more source
The activity of amyloid beta binding alcohol dehydrogenase in Alzheimer's disease
The mitochondria are a vibrant hub for many problems that occur in Alzheimer’s disease. The enzyme amyloid-ß binding alcohol dehydrogenase (ABAD) and Cyclophilin D (CypD) are two key mitochondrial proteins that have essential functions in Alzheimer’s ...
Allen, Zoe Eleanor
core

