Results 61 to 70 of about 30,484 (184)
Scientific Reports, 2021 Beauveria bassiana is a species complex whose isolates show considerable natural genetic variability. However, little is known about how this genetic diversity affects the fungus performance.
Laila Gasmi +9 more
doaj +1 more source
Informatics in Medicine Unlocked, 2022 Vaccination is a prominent strategy to confine cystic echinococcosis (CE) in areas of endemicity worldwide. The present study was performed to predict the primary biochemical features and immunogenic epitopes of Echinococcus granulosus cyclophilin ...
Sasan Khazaei, Zeinab Moghadamizad
doaj +1 more source
Assessment of Attainable Distances in Proteins by Through‐Space 19F–19F Couplings
Chemistry – A European Journal, EarlyView.De novo synthesized difluorinated tryptophan analogues are site‐specifically incorporated into Cyclophilin A (CypA). 19F–19F NOESY build‐up experiments are recorded for each labeled protein, and the distances derived from cross‐relaxation rates are compared to reference distances.
Iker Hernández +6 more
wiley +1 more source
Metrnl: A Novel Therapeutic Target in Atherosclerosis
iNew Medicine, EarlyView.ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley +1 more source
Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans [PDF]
Hepatology, 2011 Cyclophilin B (CypB) performs diverse roles in living cells, but its role in hepatocellular carcinoma (HCC) is largely unclear. To reveal its role in HCC, we investigated the induction of CypB under hypoxia and its functions in tumor cells in vitro and in vivo.
Yeonghwan, Kim +10 more
openaire +2 more sources
Human cellular restriction factors that target HIV-1 replication
BMC Medicine, 2009 Recent findings have highlighted roles played by innate cellular factors in restricting intracellular viral replication. In this review, we discuss in brief the activities of apolipoprotein B mRNA-editing enzyme 3G (APOBEC3G), bone marrow stromal cell ...
Jeang Kuan-Teh +2 more
doaj +1 more source
Frontiers in Immunology, 2020 Background: B-1a B cells and gut secretory IgA (SIgA) are absent in asplenic mice. Human immunoglobulin M (IgM) memory B cells, which are functionally equivalent to mouse B-1a B cells, are reduced after splenectomy.Objective: To demonstrate whether IgM ...
Rita Carsetti +16 more
doaj +1 more source
Immunity, Inflammation and Disease, 2022 Introduction Epstein‐Barr virus (EBV) establishes a lifelong infection in human B cells where the virus consistently expresses Latent Membrane Protein 2A (LMP2A) to promote B cell survival.
Kevin Madayag +2 more
doaj +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Mitochondrial F1FO‐ATPase is classically viewed as the “splendid” rotary nanomachine that sustains life by converting the proton‐motive force (pmf) into ATP. Yet this same complex can adopt a second, context‐dependent function that links bioenergetics to cell fate.
Salvatore Nesci
wiley +1 more source
Specific interaction of the cyclophilin-cyclosporin complex with the B subunit of calcineurin
Journal of Biological Chemistry, 1993 Calcineurin (CaN), a Ca2+/calmodulin-dependent serine/threonine phosphatase, has been shown to be inhibited by the complex of the immunosuppressant cyclosporin A (CsA) and its receptor, cyclophilin (CyP), but not by either alone. In the current study, the topological relationship between cyclophilin and the subunits of CaN has been explored using ...
W, Li, R E, Handschumacher
openaire +2 more sources