Results 21 to 30 of about 4,905 (211)

Cyclophilin-A is bound to through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex [PDF]

open access: yes, 2004
Although cyclophilin A (CyP-A) is a relatively abundant small immunophilin present in the cytoplasm of all mammalian cells, its general function(s) in the absence of the immunosuppressant drug cyclosporin A is not known.
Galigniana, Mario Daniel   +3 more
core   +2 more sources

Theileria annulata Cyclophilin1 (TaCyp1) Interacts With Host Cell MED21

open access: yesFrontiers in Microbiology, 2018
Host cells infected by Theileria annulata schizonts show the character of permanent proliferation in vitro, also named transformation. To explore the molecular mechanism a T.
Shuaiyang Zhao   +8 more
doaj   +1 more source

Structural and Functional Characterization of a Novel Family of Cyclophilins, the AquaCyps. [PDF]

open access: yesPLoS ONE, 2016
Cyclophilins are ubiquitous cis-trans-prolyl isomerases (PPIases) found in all kingdoms of life. Here, we identify a novel family of cyclophilins, termed AquaCyps, which specifically occurs in marine Alphaproteobacteria, but not in related terrestric ...
Roman P Jakob   +4 more
doaj   +1 more source

Molecular characterization of cyclophilin A-like protein from Piriformospora indica for its potential role to abiotic stress tolerance in E. coli [PDF]

open access: yes, 2013
BACKGROUND: Cyclophilins (CyP), conserved in all genera, are known to have regulatory responses of various cellular processes including stress tolerance. Interestingly, CyP has a crucial role as peptidyl-prolyl cis–trans isomerases (PPIases). Our earlier
Dipesh Trivedi   +4 more
core   +1 more source

Cyclophilin [PDF]

open access: yesScience-Business eXchange, 2011
In vitro studies suggest cyclosporine A derivatives could help treat coronaviruses such as SARS.
openaire   +1 more source

Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2 [PDF]

open access: yes, 2013
The nuclear pore complex is the sole mediator of bidirectional transport between the nucleus and cytoplasm. Nup358 is a metazoan-specific nucleoporin that localizes to the cytoplasmic filaments and provides several binding sites for the mobile ...
Hoelz, André   +4 more
core   +2 more sources

Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin

open access: yesToxins, 2018
The Bordetella pertussis toxin (PT) is one important virulence factor causing the severe childhood disease whooping cough which still accounted for approximately 63,000 deaths worldwide in children in 2013.
Katharina Ernst   +8 more
doaj   +1 more source

Cyclophilin anaCyp40 regulates photosystem assembly and phycobilisome association in a cyanobacterium

open access: yesNature Communications, 2022
Cyclophilins are proteins found in many organisms, where they can play roles as chaperones, in signal transduction, or other functions. Here, Yadav et al.
Shivam Yadav   +8 more
doaj   +1 more source

Proteomic identification of OsCYP2, a rice cyclophilin that confers salt tolerance in rice (Oryza sativa L.) seedlings when overexpressed [PDF]

open access: yes, 2011
Background High Salinity is a major environmental stress influencing growth and development of rice. Comparative proteomic analysis of hybrid rice shoot proteins from Shanyou 10 seedlings, a salt-tolerant hybrid variety, and Liangyoupeijiu seedlings, a ...
Tong Jian-Xin   +9 more
core   +2 more sources

Recombinant Cyclophilins Lack Nuclease Activity [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT Several single-domain prokaryotic and eukaryotic cyclophilins have been identified as also being unspecific nucleases with a role in DNA degradation during the lytic processes that accompany bacterial cell death and eukaryotic apoptosis. Evidence is provided here that the supposed nuclease activity of human and bacterial
Angel, Manteca, Jesus, Sanchez
openaire   +2 more sources

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