Results 91 to 100 of about 687 (168)

Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification [PDF]

, 2014
Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP.
K. Barry Sharpless, Valery V. Fokin, Fokin, Valery V, Sharpless, K Barry, Palmer Taylor, Sit, Rakesh K, Radić, Zoran, Rakesh K. Sit, Zoran Radić, Gabriel Amitai, Taylor, Palmer, Amitai, Gabriel   +11 more
core   +1 more source

Monitoring the hydrolysis of toxic organophosphonate nerve agents in aqueous buffer and in bicontinuous microemulsions by use of diisopropyl fluorophosphatase (DFPase) with H-1-P-31 HSQC NMR spectroscopy

, 2009
Gaeb J, Melzer M, Kehe K, Wellert S, Hellweg T, Blum M-M. Monitoring the hydrolysis of toxic organophosphonate nerve agents in aqueous buffer and in bicontinuous microemulsions by use of diisopropyl fluorophosphatase (DFPase) with H-1-P-31 HSQC NMR ...
Hellweg, T., Blum, M. M., Kehe, K., Gäb, J., Melzer, M., Wellert, S., Gaeb, Juergen, Wellert, Stefan, Blum, Marc-Michael, Kehe, Kai, Hellweg, Thomas ; https://orcid.org/, Melzer, Marco, Jürgen Gäb, Marc-Michael Blum, Kai Kehe, Stefan Wellert, Marco Melzer, Thomas Hellweg   +17 more
core   +1 more source

Synthesis and comparison of activity of potential reactivators of acetylcholinesterase inhibited by cyclosarine

, 2009
SYNTHESIS OF POTENCIAL QUATERNARY ACETYLCHOLINESTERASE REACTIVATORS AND EVALUATION OF THEIR POTENCY TO REACTIVATE CYCLOSARIN-INHIBITED AChE Mgr. Lukáš Lipka Department of pharmaceutical chemistry and drug control, Charles University in Prague, Faculty of
Lipka, Lukáš
core  

Detection of Chemical Warfare Agents with a Miniaturized High-Performance Drift Tube Ion Mobility Spectrometer Using High-Energetic Photons for Ionization. [PDF]

Anal Chem, 2022
Ahrens A, Allers M, Bock H, Hitzemann M, Ficks A, Zimmermann S.   +5 more
europepmc   +1 more source

Réactivité de la ß-cyclodextrine (Accès à des Epurateurs d organophosphorés neurotoxiques)

, 2010
Les armes chimiques sont encore disponibles et présentent un réel danger pour la population. Récemment, des ß-cyclodextrines ß-CD) fonctionnalisées par un dérivé de l acide 2-iodosobenzoïque ont été développées comme épurateur des organophosphorés ...
LE PROVOST, Romain, LAFONT, Olivier
core  

Detecting forensic substances using commercially available SERS substrates and handheld Raman spectrometers

, 2018
Ultra-sensitive in-field measurements of most forensic substances still today remain a challenge for first responders and forensic investigators. Handheld Raman spectroscopy equipment is getting more and more routinely used in the field for evidence ...
Stenbæk Schmidt, Michael,, Rindzevicius, Tomas, Schmidt, Michael Stenbæk, Hakonen, Aron, Boisen, Anja, Hakonen, Aron,, Andersson, Per Ola, Wu, Kaiyu, Wy, Kaiy,, Andersson, Per Ola,, Boisen, Anja,, Rindzevicius, Tomas,   +11 more
core   +1 more source

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

, 2012
The ability to redesign enzymes to catalyze noncognate chemical transformations would have wide-ranging applications. We developed a computational method for repurposing the reactivity of metalloenzyme active site functional groups to catalyze new ...
Leader, Haim, Kipnis, Yakov, Barry L Stoddard, Yakov Kipnis, Ryo Takeuchi, Moshe Goldsmith, Takeuchi, Ryo, Dan S Tawfik, Song, Yifan, Tawfik, Dan S., Khare, Sagar D., Israel Silman, David Baker, Haim Leader, Baker, David, Goldsmith, Moshe, Joel L Sussman, Stoddard, Barry L., Jasmine L Gallaher, Silman, Israel, Sagar D Khare, Greisen, Per Junior, Sussman, Joel L, Per Jr Greisen, Ashani, Yacov, Yacov Ashani, Gallaher, Jasmine L, Yifan Song   +27 more
core   +1 more source

Chemical and Biological Threats, Hazard Potential and Countermeasures. [PDF]

Toxics, 2022
Soukup O, Korabecny J.
europepmc   +1 more source

Emergency Management of Chemical Weapons Injuries

, 2011
The potential for chemical weapons to be used in terrorism is a real possibility. Classes of chemical weapons include nerve agents, vesicants (blister agents), choking agents, incapacitating agents, riot control agents, blood agents, and toxic ...
Peter D. Anderson
core   +1 more source

Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates. [PDF]

Chem Biol Interact, 2023
Lockridge O, Schopfer LM.
europepmc   +1 more source