Results 121 to 130 of about 674 (166)

Impact of Solvent Choice on SERS Sensing: Solvent-Analyte and Solvent-Substrate Effects for Organophosphate and Nerve Agent Detection. [PDF]

J Phys Chem A
Öberg R, Segervald J, Larsson A, Andersson M, Andersson PO.   +4 more
europepmc   +1 more source

Medical problems in military personnel associated with burn pit exposure: a narrative review. [PDF]

J Thorac Dis
Tran V, Shihab T, Alapati A, Nugent C, Nugent R, Nugent K.   +5 more
europepmc   +1 more source

Synthesis and Evaluation of Halogenated Pralidoximes in Reactivation of Organophosphate-Inhibited Cholinesterases. [PDF]

ACS Med Chem Lett
Knittelova K, Prchalova E, Fuchsova A, Andrys R, Kohoutova Z, Rademacherova S, Prchal L, Musilek K, Malinak D.   +8 more
europepmc   +1 more source

Environmentally Friendly Nanocoating for Rapid Detection of Nerve Agents on Textile Fabric. [PDF]

ACS Omega
Jordanov I, Dimova V, Geskovski N, Mirakovski D.   +3 more
europepmc   +1 more source

Genomic interplay between deployment exposures and Gulf War illness in Million Veteran Program participants. [PDF]

Hum Genomics
Qiu D, Cabrera-Mendoza B, He J, Steele L, Quaden R, Harrington KM, Ahmed ST, Gaziano JM, Gifford EJ, Aslan M, Helmer DA, Hauser ER, Polimanti R, Department of Veterans Affairs Cooperative Studies Program #2006 and VA Million Veteran Program.   +13 more
europepmc   +1 more source

Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats [PDF]

International Journal of Molecular Sciences, 2009
Seven new oxime-based acetylcholinesterase reactivators were compared with three currently available ones (obidoxime, trimedoxime, HI-6) for their ability to lessen cholinesterase inhibition in blood and brain of cyclosarin-treated rats. Oximes were given at doses of 5% their LD50 along with 21 mg/kg atropine five min before the LD50 of cyclosarin (120
Miroslav Pohanka, Kamil Kuca, Jiří Kassa   +2 more
exaly   +4 more sources

Reactivation of Cyclosarin-inhibited Rat Brain Acetylcholinesterase by Pyridinium–Oximes [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2004
Cyclohexyl methylphosphonofluoridate (cyclosarin, cyclosin, GF) is a highly toxic organophosphate, which is resistant to conventional oxime therapy. To gain insight into the reactivation kinetics, rat brain acetylcholinesterase (AChE) was inhibited in vitro by cyclosarin (pH 8.0, 25 degrees C) and reactivated with 22 different pyridiniumoximes.
Kamil Kuca
exaly   +3 more sources

Direct reaction of oximes with crotylsarin, cyclosarin, or VX in vitro [PDF]

Archives of Toxicology, 2006
The direct reaction of seven pyridinium oximes with the organophosphorus compounds (OPCs) crotylsarin, cyclosarin, and VX was studied by spectrophotometry. This method allows to quantify different parameters: (a) the half-life times (t (1/2)) of the oxime-OPC reactions on the basis of the changes in the absorption at the zwitterion (betaine) peak ...
Franz Worek, Ladislaus Szinicz
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Stereospecificity in the enzymatic hydrolysis of cyclosarin (GF)

Enzyme and Microbial Technology, 2005
Abstract Enzymatic catalysis is one means of accelerating the rate of hydrolysis of G-type organophosphorus nerve agents. Here, the stereospecificity of the catalysis of cyclosarin (GF, O -cyclohexyl methylphosphonofluoridate) hydrolysis by several enzymes was investigated.
Steve Harvey, Frank Raushel, Tu-Chen Cheng   +2 more
exaly   +2 more sources

Bispyridinium Oximes As Antidotal Treatment of Cyclosarin Poisoning—In Vitro and In Vivo Testing

International Journal of Toxicology, 2005
The mechanism of intoxication with organophosphorus compounds, including highly toxic nerve agents and less toxic pesticides, is based on the formation of irreversibly inhibited acetylcholinesterase, which causes cumulation of neuromediator acetylcholine in synaptic clefts and subsequent overstimulation of cholinergic receptors, that is followed by a ...
Kamil Kuca, Daniel Jun, Lucie Bartosova   +2 more
exaly   +3 more sources