Results 131 to 140 of about 1,056 (182)

Theoretical Studies Applied to the Evaluation of the DFPase Bioremediation Potential against Chemical Warfare Agents Intoxication. [PDF]

open access: yesInt J Mol Sci, 2018
Soares FV   +8 more
europepmc   +1 more source

Synthesis and Evaluation of Halogenated Pralidoximes in Reactivation of Organophosphate-Inhibited Cholinesterases. [PDF]

open access: yesACS Med Chem Lett
Knittelova K   +8 more
europepmc   +1 more source

Rapid On-Site NIR Spectroscopic Characterization of CWA Liquids Using a Novel 3D-Printed Glass Cell. [PDF]

open access: yesAnal Chem
de Koning JC   +10 more
europepmc   +1 more source

Reactivation of Cyclosarin-inhibited Rat Brain Acetylcholinesterase by Pyridinium–Oximes [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2004
Cyclohexyl methylphosphonofluoridate (cyclosarin, cyclosin, GF) is a highly toxic organophosphate, which is resistant to conventional oxime therapy. To gain insight into the reactivation kinetics, rat brain acetylcholinesterase (AChE) was inhibited in vitro by cyclosarin (pH 8.0, 25 degrees C) and reactivated with 22 different pyridiniumoximes.
Kamil Kuca
exaly   +3 more sources

Effects of low-level sarin and cyclosarin exposure on hippocampal subfields in Gulf War Veterans [PDF]

open access: yesNeuroToxicology, 2014
More than 100,000 US troops were potentially exposed to chemical warfare agents sarin (GB) and cyclosarin (GF) when an ammunition dump at Khamisiyah, Iraq was destroyed during the 1991 Gulf War (GW). We previously reported reduced hippocampal volume in GW veterans with suspected GB/GF exposure relative to matched, unexposed GW veterans estimated from 1.
Linda L Chao   +2 more
exaly   +3 more sources
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Stereospecificity in the enzymatic hydrolysis of cyclosarin (GF)

Enzyme and Microbial Technology, 2005
Abstract Enzymatic catalysis is one means of accelerating the rate of hydrolysis of G-type organophosphorus nerve agents. Here, the stereospecificity of the catalysis of cyclosarin (GF, O -cyclohexyl methylphosphonofluoridate) hydrolysis by several enzymes was investigated.
Frank M Raushel
exaly   +2 more sources

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