Results 21 to 30 of about 80,641 (196)

Cyclosporin A Decreases Human Macrophage Interleukin-6 Synthesis at Post-Transcriptional Level

Mediators of Inflammation, 1999
In addition to its well-established effect on T cells, cyclosporin A (CsA) also inhibits inflammatory cytokine production by macrophages. However, little is known about the mechanism of action of CsA on macrophage cytokine production.
Juan E. Losa García, Ana M. Rodríguez López, María Rosa Martín De Cabo, Fernando Mateos Rodríguez, Jesús Pérez Losada, Rogelio González Sarmiento, Antonio Jiménez López, José Luis Pérez Arellano   +7 more
doaj   +1 more source

Suppression of Coronavirus Replication by Cyclophilin Inhibitors

Viruses, 2013
Coronaviruses infect a variety of mammalian and avian species and cause serious diseases in humans, cats, mice, and birds in the form of severe acute respiratory syndrome (SARS), feline infectious peritonitis (FIP), mouse hepatitis, and avian infectious ...
Takashi Sasaki, Yoshikazu Tanaka, Yuka Sato   +2 more
doaj   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW, Bahnson, HT, Griffith, BP, Hakala, TR, Hardesty, RL, Ho, M, Iwatsuki, S, Jaffe, R, Nalesnik, MA, Porter, KA, Rosenthal, JT, Shaw, BW, Starzl, TE   +12 more
core   +1 more source

NEW METHOD OF DRUGS DELIVERY TO THE OCULAR SURFACE

Сибирский научный медицинский журнал, 2019
The effectiveness of topical application of various drugs in ophthalmology is no more than 3 % due to the presence of anatomical and physiological barriers.
T. N. Safonova, O. V. Gladkova, N. P. Kintyukhina   +2 more
doaj   +1 more source

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]

, 2006
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams, Aliberti, Alphey, Angus Bell, Antony P. Page, Argaet, Banerjee, Banumathy, Belfiore, Bell, Bell, Bell, Berriman, Blumenthal, Blumenthal, Borel, Bozdech, Braun, Bua, Carlton, Chakraborty, Chakraborty, Chappell, Chappell, Cianciotto, Cohen, Colgan, Dao-Thi, Denkers, Dobson, Dolinski, Dornan, Dornan, Dutta, Fischer, Florens, Galat, Galat, Gavigan, Gavigan, Gilleard, Golding, Hacker, Hall, High, Hirtzlin, Hong, Hope, Kamath, Kay, Ke, Khattab, Kiang, Klinkert, Klinkert, Knobloch, Kumar, Kumar, Kumar, Le Roch, Lightowlers, Lorberg, Ma, Ma, Ma, Matsuda, McLauchlan, Mikol, Monaghan, Monaghan, Moro, Osman, Ostoa-Saloma, Oz, Page, Page, Page, Page, Page, Page, Page, Paul Monaghan, Pelle, Pereira, Peterson, Picken, Pratt, Rascher, Reddy, Riggs, Rossi, Shirane, Silverman, Taylor, Tuo, Valle, Wang, Weiwad, Williams, Yarovinsky, Yu, Zorio   +101 more
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Modern Possibilities of Chronic Urticaria Therapy in Children

Педиатрическая фармакология, 2018
Chronic urticaria in children is one of the diseases that are underestimated in their severity and impact on the quality of life. The world academic literature data gives very little information on epidemiology, etiology of chronic urticaria, and ...
Leyla S. Namazova-Baranova, Elena A. Vishneva, Vera G. Kalugina, Anna A. Alekseeva, Yuliya G. Levina, Elena A. Dobrynina, Kamilla E. Efendieva, Konstantin S. Volkov   +7 more
doaj   +1 more source

LIVER TRANSPLANTATION FOR TYPE I GLYCOGEN STORAGE DISEASE [PDF]

, 1983
A 16½-year-old girl with type I glycogen storage disease was treated by orthotopic liver transplantation under cyclosporin/steroid immunosuppression. All metabolic stigmata of the disease were relieved and 1 year postoperatively she follows a normal diet
Alper, Alper Ca, Con, Folkman, Greene, Greene, Kashiwagi, Kashiwagi, Merrill, Nordlie, Raum, Starzl, Starzl, Starzl, Starzl, Starzl   +15 more
core   +1 more source

Effect of Cyclosporin A and Angiotensin II on cytosolic calcium levels in primary human gingival fibroblasts

Dental Research Journal, 2016
Background: To evaluate the effect of Cyclosporin A (CsA) and angiotensin II (Ang II) on cytosolic calcium levels in cultured human gingival fibroblasts (HGFs).
Ajitkumar Supraja, Murugan Girija Dinesh, Subbarayan Rajasekaran, Thodur Madapusi Balaji, Suresh Ranga Rao   +4 more
doaj   +1 more source

Successful cyclosporin and ustekinumab combination therapy in a patient with severe steroid-refractory ulcerative colitis

Therapeutic Advances in Gastroenterology, 2020
The therapeutic management of patients with severe steroid-refractory ulcerative colitis still represents a critical clinical challenge. In this setting, cyclosporin is an effective and rapidly acting induction treatment that is applied in combination ...
Ingo Ganzleben, Carol Geppert, Lourdes Osaba, Simon Hirschmann, Andreas Nägel, Christian Glück, Arthur Hoffman, Timo Rath, Daniel Nagore, Markus F. Neurath, Raja Atreya   +10 more
doaj   +1 more source

FK 506 ameliorates the hepatic injury associated with ischemia and reperfusion in rats [PDF]

, 1991
The effect of FK 506 on regeneration of the liver was studied in rats after a two‐thirds partial hepatectomy after 60 min of ischemia of the unresected liver. The animals were divided into three distinct groups of 10 rats each.
Babaeva, Bergmeyer, Borel, Craddock, Craddock, Demetris, Farber, Flye, Francavilla, Francavilla, Gonzalez, Goto, Guzek, Higgins, Kahn, Kawano, Kim, Kim, Marubayashi, Marubayashi, Mazzaferro, Mazzaferro, Meer, Metzger, Miyahara, Ohhori, Sakai, Sakai, Sakai, Sobotka, Starzl, Stromski, Takahashi, Weeds, Yushimira   +34 more
core   +1 more source