Results 21 to 30 of about 578 (154)
Plants, 2022 Cyclotides are macrocycle peptides produced by plants from several families, including Violaceae. These compounds have the potential for applications in medicine, bioengineering and crop protection thanks to their multiple biological activities.
Blazej Slazak +6 more
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Cyclotides as Tools in Chemical Biology [PDF]
Accounts of Chemical Research, 2017 Among the various molecules that plants produce for defense against pests and pathogens, cyclotides stand out as exceptionally stable and structurally unique. These ribosomally synthesized peptides are around 30 amino acids in size, and are stabilized by a head-to-tail cyclic peptide backbone and three disulfide bonds that form a cystine knot.
Simon J. de Veer +2 more
openaire +4 more sources
Structure and Activity of the Leaf-Specific Cyclotide vhl-2 [PDF]
, 2010 Cyclotides are plant-derived macrocyclic peptides with potential applications in the pharmaceutical and agricultural industries. In addition to their presumed natural function as host-defence peptides arising from their insecticidal activity, their other
Nguyencong, Philip +4 more
core +2 more sources
Cyclotide nanotubes as a novel potential Drug-Delivery System: Characterization and biocompatibility
, 2023 Cyclotides are a class of cyclic peptides that can be self-assembled. This study aimed to discover the properties of cyclotide nanotubes. We performed differential scanning calorimetric (DSC) to characterize their properties.
Ladan Dayani +11 more
core +1 more source
Frontiers in Pharmacology, 2017 Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular.
Mohsen Fahradpour +8 more
doaj +1 more source
In vitro Inhibition of HIV-1 by Cyclotide-Enriched Extracts of Viola tricolor
Frontiers in Pharmacology, 2022 Since viral infectious diseases continue to be a global health threat, new antiviral drugs are urgently needed. A unique class of therapeutic compounds are antimicrobial peptides (AMPs). They can be found in humans, bacteria and plants.
Carina Conzelmann +4 more
doaj +1 more source
On chip microfluidic separation of cyclotides
Turkish Journal of Chemistry, 2023 Cyclotides as a cyclic peptide produced by different groups of plants have been a very attractive field of research due to their exceptional properties in biological activities and drug design applications. The importance of cyclotides as new biological activities from nature caused to attract researchers to develop new separation systems.
Didarian, Reza +8 more
openaire +4 more sources
Frontiers in Plant Science, 2017 Cyclotides are a family of plant proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation.
Sungkyu Park +7 more
doaj +1 more source
, 2022 In this study, antimicrobial nanofibers were produced with the mixtures of polyvinyl alcohol (PVA) and cyclotide-rich fractions by electrospinning method.
KÜREKCİ, CEMİL +7 more
core +1 more source
Cyclotides: From Structure to Function [PDF]
Chemical Reviews, 2019 This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We include an account of their discovery, characterization, and distribution in the plant kingdom as well as a detailed analysis of their sequences and structures, biosynthesis and chemical synthesis, biological functions, and applications.
Simon J. de Veer +2 more
openaire +5 more sources