Results 61 to 70 of about 578 (154)
Exploring Plant α‐Amylase Inhibitors: Mechanisms and Potential Application for Insect Pest Control
Biotechnology Journal, Volume 20, Issue 8, August 2025.Graphical Abstract and Lay Summary In this study, we address the importance of α‐amylases in insect pests, the possible biochemical role of α‐amylase inhibitors in plant resistance to insect pests, the molecular relationships between plant α‐amylase inhibitors and insect α‐amylases, and the biotechnological potential of proteinaceous α‐amylase ...
Marcos Fernando Basso +5 more
wiley +1 more source
Cyclotides as natural anti‐HIV agents [PDF]
Peptide Science, 2008 AbstractCyclotides are disulfide rich macrocyclic plant peptides that are defined by their unique topology in which a head‐to‐tail cyclized backbone is knotted by the interlocking arrangement of three disulfide bonds. This cyclic cystine knot motif gives the cyclotides exceptional resistance to thermal, chemical, or enzymatic degradation.
Ireland, David C. +4 more
openaire +5 more sources
The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite
Scientific Reports, 2022 Plants employ different chemicals to protect themselves from herbivory. These defenses may be constitutive or triggered by stress. The chemicals can be toxic, act as repellents, phagosuppressants and/or phago-deterrents.
Blazej Slazak +11 more
doaj +1 more source
Decoding small peptides: Regulators of plant growth and stress resilience
Journal of Integrative Plant Biology, Volume 67, Issue 3, Page 596-631, March 2025.This review explores how small peptides act as key regulators of plant growth, development, and stress responses. It highlights recent advances in small peptide identification and their roles in enhancing plant resilience to environmental challenges, offering new perspectives for improving crop productivity.
Fei Xiao, Huapeng Zhou, Honghui Lin
wiley +1 more source
First cyclotide from Hybanthus (Violaceae)
, 2001 Hypa A, a novel macrocyclic polypeptide containing 30 amino acid residues, has been isolated from the n-butanol extract of the Argentine plant Hybanthus parviflorus.
Per Claeson +11 more
core +1 more source
Recombinant Production of The Cyclotide Kalata B1 by Conditional Split Inteins
ChemBioChem, Volume 26, Issue 4, February 16, 2025.A workflow to generate cyclic peptides from easily obtainable precursor proteins was established. The peptide is embedded in a split intein system that can be expressed in E. coli and purified via IMAC. Simply mixing the two precursor proteins starts conversion at will, yielding cyclic peptides.
Abdulkadir Yayci +3 more
wiley +1 more source
Optimization of the cyclotide framework to improve cell penetration properties
Frontiers in Pharmacology, 2015 Cell penetrating peptides have been regarded as promising vectors to deliver hydrophilic molecules inside cells. Although they are great tools for research and have high potential as drug delivery systems, their application as drugs is impaired by their ...
Yen-Hua eHuang +4 more
doaj +1 more source
Navigating a 1E+60 Chemical Space of Peptide/Peptoid Oligomers
Molecular Informatics, Volume 44, Issue 1, January 2025.Herein we report a virtual library of 1E+60 members, a common estimate for the size of the drug‐like chemical space. The library consists of linear or cyclic oligomers forming molecules within the size range of peptide drugs. We demonstrate ligand‐based virtual screening using a genetic algorithm.
Markus Orsi, Jean‐Louis Reymond
wiley +1 more source
Chemical and Biological Production of Cyclotides [PDF]
, 2015 Cyclotides are fascinating naturally occurring micro-proteins (≈30 residues long) present in several plant families, and display various biological properties such as protease inhibitory, anti-microbial, insecticidal, cytotoxic, anti-HIV and hormone-like activities.
Yilong, Li, Tao, Bi, Julio A, Camarero
openaire +2 more sources
Topical Delivery Systems for Plant‐Derived Antimicrobial Agents: A Review of Current Advances
International Journal of Biomaterials, Volume 2025, Issue 1, 2025.Plant‐derived compounds have attracted considerable attention in the field of antimicrobial therapy. This interest is primarily due to their natural origin and historical evidence of their use in traditional medicine systems. These derivatives are a rich reservoir of chemical diversity that has a promising potential for the development and production ...
Mohammad Hashem Hashempur +10 more
wiley +1 more source