Results 161 to 170 of about 4,091 (215)

Benthic cyanobacterial accumulations and associated cyanotoxins in coastal urban stormwater pond networks. [PDF]

Harmful Algae
Tatters AO, Clevenger C, Strangman WK, Oehrle S, Kudela RM, Aukamp J, Wan Y.   +6 more
europepmc   +1 more source

Development of a Multiplexed Electrochemical Aptasensor for the Detection of Cyanotoxins. [PDF]

Biosensors (Basel)
Rhouati A, Zourob M.
europepmc   +1 more source

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Identification of 7-Deoxy-desulfo-argino-cylindrospermopsin, the Missing Piece in Cylindrospermopsin Biosynthesis

Journal of the American Chemical Society, 2022
Cylindrospermopsin, a major cyanotoxin, is produced by freshwater cyanobacteria. Its biosynthesis starts from arginine and glycine and involves five polyketide synthases and several tailoring enzymes. We report the identification of 7-deoxy-desulfo-argino-cylindrospermopsin in several cylindrospermopsin-producing cyanobacteria using mass spectrometry ...
Méjean, Annick, Lequin, Olivier, Ploux, Olivier   +2 more
openaire   +2 more sources

Biosynthesis of Cylindrospermopsin

The Journal of Organic Chemistry, 1999
Studies on the biosynthesis of cylindrospermopsin (1), a potent hepatotoxin associated with the cyanobacterium Cylindrospermopsis raciborskii, indicate that 1 is an acetogenin with guanidinoacetic acid serving as the starter unit of the polyketide chain. Feeding experiments show that C14 and C15 of 1 are derived from C1 and C2 of glycine, respectively,
D L, Burgoyne, T K, Hemscheidt, R E, Moore, M T, Runnegar   +3 more
openaire   +3 more sources

Investigating the production and release of cylindrospermopsin and deoxy-cylindrospermopsin by Cylindrospermopsis raciborskii over a natural growth cycle

Harmful Algae, 2014
Many harmful cyanobacterial genera have strains that can produce potent toxins and other biologically active compounds that present a risk to the health of humans and other animals that consume or contact contaminated water. Cylindrospermopsins (CYNs) are produced by several species of cyanobacteria including Cylindrospermopsis raciborskii (Woloszynska)
Gregory L Boyer, Michele A Burford, Philip T Orr   +2 more
exaly   +11 more sources

Characterization of cylindrospermopsin chlorination

Science of The Total Environment, 2010
In temperate countries, the occurrence of cyanobacterial blooms threatens drinking water resources. Consequently, cyanotoxins are increasingly considered in water treatment, and their reactions with chlorine used to disinfect drinking water are particularly investigated.
Merel, Sylvain, Clément, Michel, Mourot, Annick, Fessard, Valérie, Thomas, Olivier   +4 more
openaire   +2 more sources

A biomimetic approach to the cylindrospermopsin alkaloids

Chemical Communications, 2011
The tethered Biginelli condensation between hemiaminal 21 and β-keto ester 22 is reported, leading to a model tricyclic core of the cylindrospermopsin alkaloids.
Daniel M, Evans, Patrick J, Murphy
openaire   +2 more sources

The Cylindrospermopsin Alkaloids

2011
Abstract The cylindrospermopsin alkaloids are a family of structurally similar toxic natural products first encountered with the isolation of cylindrospermopsin from the cyanobacterium Cylindrospermopsis raciborskii , which was the causative agent in the poisoning of 148 inhabitants of Palm Island, Australia.
Daniel M, Evans, Patrick J, Murphy
openaire   +2 more sources

Total Synthesis of (±)-Cylindrospermopsin

Journal of the American Chemical Society, 2000
The first total synthesis of the novel hepatotoxin (±)-cylindrospermopson (1) has been accomplished in 20 steps from 4-methoxy-3-methylpyridine (12) in 3.5% overall yield. The substituted piperidine A ring 19 was generated stereospecifically by a four-step sequence using the addition of trimethylsilylethynylmagnesium bromide to 12 to give 16 and ...
Chaoyu Xie, Maria T. C. Runnegar, Barry B. Snider   +2 more
openaire   +1 more source