Results 101 to 110 of about 13,126 (201)
, 2015 The aim of this study was to investigate the gene and genotype distributions of some mutations in the aromatase cytochrome P450 (CYP19), estrogen receptor alpha (ER alpha), and progesterone receptor (PGR) genes in fertile and subfertile Holstein-Friesian
Güner, Barış +6 more
core +1 more source
Association of SNP rs.2414096 CYP19 gene with polycystic ovarian syndrome in Iranian women
International Journal of Reproductive BioMedicine, 2017 Background: Genetic factors are believed to play an important role in the etiology of polycystic ovarian syndrome (PCOS) which is the most common endocrinological disorder of women in their reproductive age.
Anahita Mehdizadeh +4 more
doaj
The nucleosome occupancy in the CYP19 locus.
, 2015 (A-C) ChIP assays with anti-pan-histone H3 revealed the amount of nucleosomes in the CYP19 locus in HepG2 (A), KGN (B), or HeLa cells (C). The nucleosome level is expressed as a percentage of total input chromatin (IP/Input).
Naoe Kotomura (746485) +2 more
core +1 more source
, 2016 Postmenopausal women are at high risk for cardiovascular diseases because of the estrogen deficiency. As for postmenopausal breast cancer patients, this risk is even higher due to inhibition of estrogens biosyntheses in peripheral tissue by the aromatase
Qingzhong Hu (124547) +2 more
core +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2015 Background: A series of biochemical reactions are involved in the endogenous production of estrogens. Their final and rate-limiting step is catalyzed by aromatase belonging to the class XIX of cytochrome P450. CYP19 is a key enzyme for estrogen synthesis
KH Onsory +3 more
doaj
CYP19 VNTR POLYMORPHISM A RISK FACTOR IN ENDOMETRIOSIS [PDF]
, 2009 Endometriosis is defined by the presence of endometrial glands and stroma outside of the uterine cavity. Although the exact aetiology and pathogenesis is unclear, both environmental and genetic factors have been implicated in the disease.
Hidayat , Syarif T +2 more
core
فصلنامه دانشگاه علوم پزشکی جهرم, 2018 Background and aims: CYP17A1 and CYP19A2 enzymes are key proteins in constructing and regulating steroid hormones such as cortisol, testosterone and estrogen. But the effect of exercise on these two proteins in ovary tissue has not been investigated yet.
maryamosadat miri +4 more
doaj
The polymorphisms of the CYP17 and CYP19 genes in endometrial cancer patients.
Polish journal of pathology : official journal of the Polish Society of Pathologists, 2006 Endogenous estrogen exposure is an important determinant of endometrial cancer risk. The CYP 17 and CYP 19 genes encode 17alphahydroxylase/17,20-lyase and aromatase, respectively, both involved in sex hormone synthesis. The genes CYP17 and CYP19 are polymorphic and gene variability could contribute to the level of protein biosynthesis.
Krzysztof, Szyłło +3 more
openaire +1 more source
Neonicotinoids induce a promoter-switch in CYP19 expression in breast-cancer cells and alter aromatase activity and hormone production in a feto-placental co-culture model [PDF]
, 2016 In estrogen-dependent breast cancer, CYP19 expression is increased via activation of several promoters (PII, I.3, I.7) and by the inhibition of normal I.4 promoter.
Denison, Michael S. +2 more
core
VISFATIN: a novel modulator of placental endocrinology under physiological and pathological conditions-in vitro studies involving INSR, ERK1/2, and PKA signalling pathways. [PDF]
Sci RepDawid M, Gieras W, Milewicz T, Rak A.
europepmc +1 more source