Results 81 to 90 of about 13,126 (201)

Screening of a panel of steroid-related genes showed polymorphisms of aromatase genes confer susceptibility to advanced stage endometriosis in the Taiwanese Han population

Taiwanese Journal of Obstetrics & Gynecology, 2013
Objective: To establish a multilocus model for studying the effect of steroid-related genes on advanced stage endometriosis. Materials and methods: A total of 121 patients with advanced stage endometriosis and 171 control women were included.
Cheng-Hsuan Wu, Jyuer-Ger Yang, Yu-Jun Chang, Chao-Chin Hsu, Pao-Lin Kuo   +4 more
doaj   +1 more source

Enhancing the Anticancer Efficacy of Polyphenols Through Lipid‐Based and Polymeric Nanoparticle Delivery Systems in Triple‐Negative Breast Cancer (TNBC)

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Breast cancer is the most common cancer among women. Triple‐negative breast cancer (TNBC) lacks hormone receptors and human epidermal growth factor receptor 2 expression and has aggressive behavior and poor prognosis; therefore, it has significant limitations and challenges in its treatment.
Nooshin Goudarzi, Ensiyeh Bahadoran, Masood Alaei, Kimia Taebi, Arian Ashrafzadeh, Arash Keshavarz Shahbaz, Sanaz Keshavarz Shahbaz, Munmun Bardhan   +7 more
wiley   +1 more source

Interaction of Perfumes with Cytochrome P-450 19

Cosmetics
Cytochrome P450 (CYP) enzymes play a key role in the metabolism of foreign compounds and in the biosynthesis and catabolism of endogenous substances, including hormones.
Iva Drejslarová, Tomáš Ječmen, Petr Hodek   +2 more
doaj   +1 more source

Epigenetic Modifications Influence Reproductive Traits in Small Ruminants

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
The epigenome undergoes dynamic changes shaped by the intricate interplay of genetic and environmental factors, which are crucial for individual growth and development. Recent studies suggest that factors such as nutrition, thermal stress (TS), infections, and assisted reproductive technologies (ARTs) can influence epigenetic changes in small ruminants
Galma Boneya Arero, Ozge Ozmen, Lipi Buch   +2 more
wiley   +1 more source

Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish Chromosomes Are Expressed in Ovary or Brain [PDF]

, 2001
International audienceCytochrome P450 aromatase (Cyp19) is an enzyme catalyzing the synthesis of estrogens, thereby controlling various physiological functions of estrogens.
Guiguen, Yann, Evelyn Feng-Lin Chiang, Yann Guiguen, Feng-Lin Chiang, Evelyn, Postlethwait, John, Yi-Lin Yan, John Postlethwait, Yan, Yi-Lin, Chung, Bon-Chu, Bon-chu Chung   +9 more
core   +1 more source

(TTTA)n polymorphism of CYP19 (aromatase gene) in Euro- and Afro-Brazilians

Genetics and Molecular Biology, 2004
We investigated the polymorphic tetranucleotide repeat (TTTA)n located in the fourth intron of the CYP19 gene in two Brazilian populations. The frequencies of the five common alleles (A) in Euro- and Afro-Brazilians were, respectively: seven repeats (A5),
Kátia Kvitko, Janice Corrêa de Barros Nunes, Mara Helena Hutz   +2 more
doaj   +1 more source

Aromatase (CYP19) gene variants influence ovarian response to standard gonadotrophin stimulation

, 2012
PURPOSE: The association of cytochrome P450 aromatase gene CYP19(TTTA) ( n ) polymorphism with ovarian response to FSH stimulation was explored. METHODS: Three hundred women undergoing medically assisted reproduction and 300 women with at least one ...
Takenaka, A., Kosmas, I. P., Zikopoulos, K. A., Sofikitis, N. V., Xita, N. V., Lazaros, L. A., Makrydimas, G. V., Hatzi, E. G., Stefos, T. I., Georgiou, I. A., Kaponis, A. I.   +10 more
core  

Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research

Environmental Health, 2009
Background CYP19 and PPARγ are two genes expressed in the placental trophoblast that are important to placental function and are disrupted by phthalate exposure in other cell types.
Nelson Heather, Thaker Harshwardhan M, Whyatt Robin M, Williams Paige L, Hauser Russ, Adibi Jennifer J, Herrick Robert, Bhat Hari K   +7 more
doaj   +1 more source

Relationship of CYP19 genotypes (CC + AC vs AA) with clinical characteristics.

, 2015
1 Two-sided χ2 test.Relationship of CYP19 genotypes (CC + AC vs AA) with clinical characteristics.
Yong Guo (169213), Xiaohong Xu (180651), Jian Huang (7250), Xiying Shao (707375), Jufen Cai (707377), Xiaojia Wang (218810), Jiwen Wang (4824936), Zhanhong Chen (707376), Ping Huang (30439), Yabing Zheng (104760)   +9 more
core   +1 more source

Editing the CYP19 Gene in Goat Embryos Using CRISPR/Cas9 and Somatic Cell Nuclear Transfer Techniques

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) system is revolutionizing genome engineering and is expected to bring significant advancements in livestock traits, including the treatment of genetic diseases.
Kues, Wilfried, Izadi, Tayebeh, Nasr-Esfahani, Mohammad-Hossein, Safaeinejad, Zahra, Rahimi Andani, Mohsen, Jafarpour, Farnoosh, Tanhaie-vash, Nima, Hosseini Moghaddam, Seyed Hossein, Shiralian-Esfahani, Hanieh, Pirali, Ahmad, Eghbalsaied, Shahin, Hajian, Mehdi, Moradi, Reza   +12 more
core   +1 more source