Results 71 to 80 of about 13,126 (201)
Фундаментальная и клиническая медицина, 2018 Aim. To estimate whether CYP1A1, CYP1A2, CYP19, SULT1A1 gene polymorphisms are associated with genital endometriosis in infertile women. Materials and Methods.
LARISA N. Danilova +3 more
doaj
Insights Into Infections and Inflammation in Prostate Cancer Development and Management: An Overview
BioMed Research International, Volume 2026, Issue 1, 2026.Prostate cancer (PCa) represents a major public health concern and continues to be one of the leading causes of cancer‐related mortality among men worldwide. Current epidemiological projections suggest that the incidence and associated burden of PCa are likely to increase, emphasizing the importance of advancing preventive measures, improving early ...
Ensiyeh Bahadoran +6 more
wiley +1 more source
International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.Background Breast cancer (BC) is the most common malignancy among women, with 2.3 million new cases and over 670,000 deaths annually. Despite advances in detection and therapy, relapse, metastasis, and resistance remain significant challenges. Tumor suppressor genes (TSGs) regulate abnormal cell division, whereas oncogenes, which arise from proto ...
Md. Sadikuj Jaman +4 more
wiley +1 more source
17-Hydroexemestane: A Potent Inhibitor of CYP19 (Aromatase) and Substrate of CYP3A
, 2014 17-hydroexemestane is the major metabolite of exemestane in vivo. Previous studies have shown that 17-hydroexemestane is androgenic and bone protective.
David, F A +2 more
core +1 more source
Indonesian Journal of Biotechnology, 2015 Soybean (Glycine max L. Merr.) contains phytoestrogens that have a chemical structure resembling estrogen in the body. They function like estrogen and antiestrogen, affecting the metabolism of sex steroid hormones.
Retno Aryani +3 more
doaj +1 more source
Exploring the Expanding Role of Nuclear Receptor LRH‐1/NR5A2 in Cell Biology and Immunity
International Journal of Cell Biology, Volume 2026, Issue 1, 2026.LRH‐1/NR5A2 is a member of the NR5A subfamily of nuclear receptors, acting as a crucial transcription factor involved in diverse biological processes. Although LRH‐1 has been extensively studied in vitro and in vivo, in relation to its role in embryonic development and differentiation and in adult tissue processes, such as cholesterol, glucose, and ...
Eleni Tsapalou +6 more
wiley +1 more source
Evaluation of reproductive activity of Tsc1flox/flox;cyp19-cre mice.
, 2013 (A) Tsc1flox/flox; cyp19-cre mice produced more pups than wild type mice. (B) The average litter size of Tsc1flox/flox; cyp19-cre mice was bigger than that of the wild type.
Zong-Zhe Jiang (288601) +11 more
core +1 more source
Review of Imidazole Derivatives as Aromatase Inhibitors
Journal of Chemistry, Volume 2026, Issue 1, 2026.Breast cancer (BC) is the most commonly diagnosed malignancy in women globally, accounting for over 11% of all new cancer cases in female patients. Hormone receptor–positive BC relies on estrogen‐driven growth, making endocrine therapy a cornerstone of treatment. The standard clinical approach typically involves tamoxifen, a selective estrogen receptor
Haitham Al-Madhagi
wiley +1 more source
Correlation of CYP19 polymorphism (CC vs AC vs AA) to clinical characteristics.
, 2015 1Two-sided χ2 test.Correlation of CYP19 polymorphism (CC vs AC vs AA) to clinical characteristics.
Yong Guo (169213) +9 more
core +1 more source
Effects of Neonicotinoids on Promoter-Specific Expression and Activity of Aromatase (CYP19) in Human Adrenocortical Carcinoma (H295R) and Primary Umbilical Vein Endothelial (HUVEC) Cells. [PDF]
, 2015 International audienceThe enzyme aromatase (CYP19; cytochrome P450 19) in humans undergoes highly tissue- and promoter-specific regulation. In hormone-dependent breast cancer, aromatase is over-expressed via several normally inactive promoters (PII, I.3,
Caron-Beaudoin, Élyse +5 more
core +1 more source