Results 61 to 70 of about 13,126 (201)

Association between CYP19 gene SNP rs2414096 Polymorphism and polycystic ovary syndrome in Chinese women

open access: yesBMC Medical Genetics, 2009
Background Several studies have reported the association of the SNP rs2414096 in the CYP19 gene with hyperandrogenism, which is one of the clinical manifestations of polycystic ovary syndrome (PCOS).
Yi Long   +10 more
doaj   +1 more source

Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects. [PDF]

open access: yesPLoS ONE, 2013
Lifetime exposure to estrogen is a factor that plays an important role in the pathogenesis and progression of breast cancer. Genetic variants in genes of the biosynthesis and metabolism of estrogen have been associated with breast cancer risk. Among them,
Begoña Pineda   +4 more
doaj   +1 more source

Identification of SF-1 and FOXL2 and Their Effect on Activating P450 Aromatase Transcription via Specific Binding to the Promoter Motifs in Sex Reversing Cheilinus undulatus

open access: yesFrontiers in Endocrinology, 2022
The giant wrasse Cheilinus undulatus is a protogynous socially hermaphroditic fish. However, the physiological basis of its sex reversal remains largely unknown.
Xinxin Ji   +6 more
doaj   +1 more source

Inflammation and Oxidative Stress in Male Infertility: A Narrative Review

open access: yesReproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Background Male infertility affects 8%–15% of couples, with male factors implicated in about half of cases; many remain idiopathic despite improved diagnostics. This narrative review addresses this gap by examining chronic inflammation as an underappreciated driver of sperm dysfunction that forms a bidirectional, self‐reinforcing cycle with ...
Donya Pourbagher   +5 more
wiley   +1 more source

Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish

open access: yes, 2008
Many natural and synthetic compounds present in the environment exert a number of adverse effects on the exposed organisms, leading to endocrine disruption, for which they were termed endocrine disrupting chemicals (EDCs).
Segner, Helmut   +14 more
core   +1 more source

The relationship between the CYP19 alleles rs727479A/C, rs700518A/G, and rs700519C/T and pregnancy outcome after assisted reproductive technology in patients with polycystic ovary syndrome in a Chinese population: A population-based study

open access: yesKaohsiung Journal of Medical Sciences, 2017
This study investigated the relationship between the CYP19 alleles, rs727479A/C, rs700518A/G, and rs700519C/T, and pregnancy outcome after assisted reproductive technology (ART) in patients with polycystic ovary syndrome (PCOS).
Qian Dou   +3 more
doaj   +1 more source

Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.
Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli   +12 more
wiley   +1 more source

Wpływ SNP w genie CYP19 na cechy użytkowości mlecznej krów jersey [PDF]

open access: yes, 2013
The aim of this study was to examine the relationship between genotype two SNPs located in the promoter region of CYP19 gene and milk production traits. The study included 181 Jersey cows. The genotypes were identified by the PCRRFLP method.
Kowalewska-Luczak, I.   +2 more
core  

Polychlorinated biphenyl exposure and CYP19 gene regulation in testicular and adrenocortical cell lines

open access: yes, 2008
[[abstract]]Exposure to polychlorinated biphenyls (PCBs) disturbs many estrogen-mediated biochemical processes. PCBs may cause these abnormalities by altering expression of the aromatase gene CYP19.
Li, LA
core   +1 more source

The Role of Anethole in Reproductive Physiology and In Vitro Biotechnologies—A Review

open access: yesReproduction in Domestic Animals, Volume 61, Issue 1, January 2026.
ABSTRACT In vitro reproductive biotechnologies show promise for fertility preservation but still face challenges, including oxidative stress from high oxygen tension, which impairs cell viability and development. Antioxidants have been widely explored to attenuate oxidative stress during culture.
André Luiz da Conceição‐Santos   +1 more
wiley   +1 more source

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