Results 41 to 50 of about 13,126 (201)
The effects of the standardized extracts of on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells [PDF]
Environmental Health and Toxicology, 2016 Objectives Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic effects like the ...
Mijie Kim +5 more
doaj +1 more source
Ovulation is impaired in Egfrf/f Cyp19-Cre and Egfrdelta/f Cyp19-Cre mice.
, 2013 A and C, When super-ovulated, Egfrf/f Cyp19-Cre and Egfrdelta/f Cyp19-Cre mice released significantly fewer oocytes into the oviducts than WT females. The greater the disruption of Egfr expression in mice, the fewer the number of oocytes ovulated.
Minnie Hsieh (348774) +2 more
core +1 more source
Steroidogenic Enzyme and Steroid Receptor Expression in the Equine Accessory Sex Glands
Animals, 2021 The expression pattern and distribution of sex steroid receptors and steroidogenic enzymes during development of the equine accessory sex glands has not previously been described.
Robyn E. Ellerbrock +5 more
doaj +1 more source
EFFECT OF CYP19 GENE ON POLYCYSTIC OVARY SYNDROME PHENOTYPE IN IRAQI WOMEN
The Iraqi Journal of Medical Sciences, 2016 Background:Ovarian androgen overproduction is the key physiopathologic feature of polycystic ovary syndrome and the bulk of evidence points to the ovary being the source of excess androgens, which appears to result from an abnormal regulation ...
Manal T. Mutib +2 more
doaj +4 more sources
Journal of Pharmacological Sciences, 2004 The present study was designed to determine the mechanisms by which serum estradiol levels are enhanced during gonadotropin-induced ovarian development in hypothyroid immature rats.
Minoru Hatsuta +4 more
doaj +1 more source
Hayati Journal of Biosciences, 2021 Anadara clam shell contains high Zinc. This microelement is recognised as acting natural aromatase blocker (NAB) that capable of boosting testosterone level.
Pudji Astuti +5 more
doaj +1 more source
npj Vaccines, 2023 Human infection with the protozoan parasite Trypanosoma cruzi causes Chagas disease for which there are no prophylactic vaccines. Cyclophilin 19 is a secreted cis-trans peptidyl isomerase expressed in all life stages of Trypanosoma cruzi. This protein in
Bijay Kumar Jha +11 more
doaj +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.Potentially toxic elements impair male reproductive function through oxidative stress, DNA damage, mitochondrial dysfunction, inflammation, endocrine disruption and epigenetic alterations. Antioxidants, phytochemicals, chelating agents and healthy lifestyle interventions may help mitigate testicular toxicity and preserve fertility.
Sakshi Yadav, Placheril J John
wiley +1 more source
Cytochrome P450 aromatase gene (CYP19) expression in gastric cancer [PDF]
Gastric Cancer, 2008 The secretion of biologically active estrogen through the conversion of circulating precursor androgens has been suggested to play important roles in the pathophysiology of estrogen-dependent carcinomas. In the present study, we examined aromatase expression in gastric carcinoma.Nineteen specimens of gastric carcinoma were obtained from Japanese ...
Masao, Izawa +6 more
openaire +2 more sources
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
eFood, Volume 7, Issue 4, August 2026.Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source