Results 31 to 40 of about 13,126 (201)
Polymorphisms of CYP1A1, CYP1A2, CYP19, and SULT1A1 genes in women with early miscarriage
Фундаментальная и клиническая медицина, 2019 Aim. To determine the frequency of the polymorphisms within the genes encoding estrogen metabolism enzymes: CYP1A1 (rs4646903), CYP1A2 (rs762551), CYP19 (rs700519) and SULT1A1 (rs9282861) in women with early miscarriage.Materials and Methods.
I. N. Noskova +2 more
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Majalah Kedokteran Gigi Indonesia, 2016 Latar Belakang. Estrogen mengatur homeostasis tulang dan disekresikan oleh gonad dan ekstragonad. Selain itu,androgen diubah menjadiestrogen oleh enzim aromatase P450 yang dihasilkan oleh sitokrom P450 aromatase.
Dahlia Herawati +3 more
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The Effects of Exercise on Expression of CYP19 and StAR mRNA in Steroid-Induced Polycystic Ovaries of Female Rats [PDF]
International Journal of Fertility and Sterility, 2018 Background: Polycystic ovarian syndrome (PCOS) is the most frequent female endocrine disorder that affects 5-10% of women. PCOS is characterized by hyperandrogenism, oligo-/anovulation, and polycystic ovaries.
Fatemeh Aghaie +3 more
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Specific disruption of Tsc1 in ovarian granulosa cells promotes ovulation and causes progressive accumulation of corpora lutea. [PDF]
PLoS ONE, 2013 Tuberous sclerosis complex 1 (Tsc1) is a tumor suppressor negatively regulating mammalian target of rapamycin complex 1 (mTORC1). It is reported that mice lacking Tsc1 gene in oocytes show depletion of primordial follicles, resulting in premature ovarian
Lin Huang +11 more
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The genomic environment around the Aromatase gene: evolutionary insights
BMC Evolutionary Biology, 2005 Background The cytochrome P450 aromatase (CYP19), catalyses the aromatisation of androgens to estrogens, a key mechanism in vertebrate reproductive physiology. A current evolutionary hypothesis suggests that CYP19 gene arose at the origin of vertebrates,
Reis-Henriques Maria A +2 more
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Journal of Genetic Engineering and Biotechnology, 2023 Background Polycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19 gene encodes key enzyme aromatase involved in androgen-to-estrogen conversion which plays a crucial role in
Pravesh Hegde +5 more
doaj +1 more source
Variable Phenotypes Associated with Aromatase (CYP19) Insufficiency in Humans [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2007 The P450 enzyme aromatase (CYP19) plays a crucial role in the endocrine and paracrine biosynthesis of estrogens from androgens in many diverse estrogen-responsive tissues. Complete aromatase deficiency has been reported in a small number of 46,XX girls with genital ambiguity and absent pubertal development, but it is unknown whether nonclassic ...
Lin +7 more
openaire +4 more sources
Scientific Reports, 2021 Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder in pre-menopausal women having complex pathophysiology. Several candidate genes have been shown to have association with PCOS.
Sairish Ashraf +5 more
doaj +1 more source
Effect of e-cigarette refill liquid on follicular development and estrogen secretion in rats
Tobacco Induced Diseases, 2022 Introduction Electronic cigarettes (e-cigarettes) have recently become popular as an alternative to conventional cigarettes. The aim of this study is to investigate the effects of e-cigarette refill liquid (e-liquid) on follicular development and ...
Tairen Chen +8 more
doaj +1 more source
Single Nucleotide Polymorphisms in the Promoter of CYP19 Gene in Cattle Bred in Iraq
Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ, 2020 The present study was undertaken to characterize the genetic diversity of the aromatase cytochrome P450 (CYP19) gene in 34 cows (15 local, 14 Holstein, and 5 Crosses) in Iraq. The objectives of the present study are to detect SNPs (mutations) in promoter
Salah H. Faraj +2 more
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