Results 151 to 160 of about 13,126 (201)
Benefits of aromatase blockers for increased testosterone in poultry: A mini-review. [PDF]
Vet WorldYuneldi RF +4 more
europepmc +1 more source
Genetic variants of CYP19 (aromatase) and breast cancer risk [PDF]
Oncogene, 2000 The effect of a SNP in exon 10 of CYP19 on tumor mRNA levels and splice variants were studied and correlated with clinical parameters and risk of breast cancer. In the vast majority of breast cancers, the estrogen levels modulate the tumor growth and depend on the activity of CYP19.
Tom Kristensen, Per Eystein Lønning
exaly +4 more sources
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CYP19 gene polymorphism in endometrial cancer patients
Journal of Cancer Research and Clinical Oncology, 2001Initiation/promotion of endometrial cancer is known to be associated with estrogenic influence. Therefore, it is possible that some allelic polymorphisms of the genes involved in steroidogenesis or steroid metabolism contribute to endometrial cancer susceptibility.Here, we compared CYP19 (aromatase) gene polymorphism in 85 endometrial cancer patients ...
Evgeny N Suspitsin +2 more
exaly +3 more sources
Analysis of zebrafish cyp19 promoters
The Journal of Steroid Biochemistry and Molecular Biology, 2003Cyp19 encodes P450 aromatase, the key enzyme catalyzing the conversion of androgens into estrogens. Estrogens play a crucial role in the anatomical, functional and behavioral characteristics of sexually dimorphic development. In zebrafish, two cyp19 genes, cyp19a and cyp19b, expressed in ovary and brain, respectively, were found.
Sok-Keng, Tong, Bon-chu, Chung
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International Journal of Molecular Sciences, 2020 Estrogen overproduction is closely associated with the development of estrogen receptor-positive breast cancer. Aromatase, encoded by the cytochrome P450 19 (CYP19) gene, regulates estrogen biosynthesis.
Soon Young Shin +2 more
exaly +2 more sources
Characterization of duplicated zebrafish cyp19 genes
Journal of Experimental Zoology, 2001AbstractThe zebrafish has recently been developed as a good genetic model system. We report here the use of zebrafish to study the regulation of estrogen biosynthesis. The CYP19 gene encodes cytochrome P450 aromatase, which catalyzes the synthesis of estrogens. Two cyp19 genes, termed cyp19a and cyp19b, have been isolated from zebrafish.
Chiang, E.F.L. +6 more
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CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype
Fertility and Sterility, 2010 To evaluate the possible contribution of the (TTTA)n polymorphism of aromatase gene (CYP19) to the hyperandrogenic phenotype of polycystic ovary syndrome (PCOS).Case-control study.Endocrine outpatients' clinic of a tertiary university hospital.One hundred eighty women with PCOS and 160 healthy controls of reproductive age.Blood sampling for genotype ...
Ioannis Georgiou +2 more
exaly +4 more sources