Results 91 to 100 of about 6,856 (158)

Determination of CYP27a1 in biological samples using nano liquid chromatography mass spectrometry

, 2016
The cytochrome P450 enzyme, CYP27a1, converts cholesterol into 27-hydroxycholesterol, and both the metabolite and the enzyme are associated with breast cancer, promoting proliferation and metastasis.
Sæterdal, Kristina Erikstad
core  

Protein expression of CYP27A1 and CYP2R1 in hGF and hPDLC.

, 2013
Protein expression of CYP27A1 was detected by Western blot in hGF and hPDLC from all five donors (donors are numbered 1–5). Protein expression of CYP2R1 was detected by Western blot in PC-3 cells, which were used as a positive control, but was not ...
Jianxia Hou (294610), Kaining Liu (294608), Huanxin Meng (294609)   +2 more
core   +1 more source

Expression of CYP27A1 and CYP2R1 mRNA in hGF and hPDLC.

, 2013
Expression of CYP27B1 mRNA was detected by real-time PCR in hGF and hPDLC from all five donors (donors are numbered 1–5). The expression levels of CYP27A1 and CYP2R1 mRNA were not significantly different in the two kinds of cells.
Jianxia Hou (294610), Kaining Liu (294608), Huanxin Meng (294609)   +2 more
core   +1 more source

Supplementary Materials and Methods from CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer

, 2017
Reagents and cell culture conditions. Methods for bioinformatics analysis, CYP27A1 IHC, caspase assays and 27HC measurements.
Erik R. Nelson (12035807), Michael R. Freeman (153526), Mahmoud A. Alfaqih (14928213), Everardo Macias (14884124), Rachid Safi (81663), Jeffery S. Jasper (14928216), Stephen J. Freedland (7926608), Laura G. Dubois (562976), Wen Liu (39804), J. Will Thompson (202608), Donald P. McDonnell (15299), Jen-Tsan Chi (48985), Ching-yi Chang (15295), Joseph Geradts (65246)   +13 more
core   +1 more source

Increased Maternal and Fetal Cholesterol Efflux Capacity and Placental CYP27A1 Expression in Pre-eclampsia.

, 2017
Pre-eclampsia is a pregnancy-specific condition, leading to increased cardiovascular risk in later life. A decrease in cholesterol efflux capacity is linked to cardiovascular disease.
Escher, Geneviève, Kurlak, Lesia O, Mohaupt, Markus, Mansour, Yosef T, Zurkinden, Line, Mistry, Hiten Dhirubhai   +5 more
core   +1 more source

Targeted sequencing provides genetic insights into familial cardiovascular disease among young adults in a high consanguinity population. [PDF]

PLoS One
Arif N, Khan I, Khan TA, Ahmad S, Nauman F, Ahmad G, Ijaz M, Ahmad B, Hassan SM, Afaq S, Haq ZU.   +10 more
europepmc   +1 more source

Genetics of Cerebrotendinous Xanthomatosis. [PDF]

Mol Diagn Ther
Hanson J, Bonnen PE.
europepmc   +1 more source

Electro-scalp acupuncture regulates the expression of CYP27a1/b1， CYP24a and related inflammatory cytokines in ischemic cortex of rats with middle cerebral artery occlusion

针刺研究
ObjectiveTo observe the effect of electro-scalp acupuncture （ESA） on the expression of cytochrome P450a1/b1 （CYP27a1/b1）， cytochrome P45024a （CYP24a）， signal transducer and activator of transcription （STAT）4， STAT6， tumor necrosis factor-α （TNF-α ...
ZHANG Shan-yu, YUAN Bo, LUO Wen-jun, ZHU Ling-gui, ZHANG Yan-ju, TIAN Tian, PENG Xiao-yun, WANG Jin-hai   +7 more
doaj   +2 more sources

Beyond VDR: Vitamin D Metabolism Genes in Tuberculosis Susceptibility, Immune Response and Implications for Diabetes Mellitus. [PDF]

Infect Drug Resist
Rabadi M, Hussain Z, Siddiqui SF, Siddiqui HF, Nomikos M, Seed Ahmed M.   +5 more
europepmc   +1 more source

Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation. [PDF]

Exp Dermatol
Zhu A, Yang L, Lai S, Yang F, Tsuruta D, Katayama I.   +5 more
europepmc   +1 more source