Cathelicidin preserves intestinal barrier function in polymicrobial sepsis. [PDF]
ObjectivesThe intestinal epithelium compartmentalizes the sterile bloodstream and the commensal bacteria in the gut. Accumulating evidence suggests that this barrier is impaired in sepsis, aggravating systemic inflammation. Previous studies reported that
Chan, Hung +22 more
core +1 more source
Evidence linking exposure of fish primary macrophages to antibiotics activates the NF-kB pathway. [PDF]
Low doses of antibiotics are ubiquitous in the marine environment and may exert negative effects on non-target aquatic organisms. Using primary macrophages of common carp, we investigated the mechanisms of action following exposure to several common ...
Chen, Qiqing +8 more
core
Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
Caridis, Anna-Maria +3 more
core +1 more source
Retinal pigment epithelium cholesterol efflux mediated by the 18kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration [PDF]
Biswas, Lincoln +4 more
core +2 more sources
A new CYP27A1 mutation in a case of cerebrotendinous xanthomatosis
S.Y. Zhang +3 more
openaire +2 more sources
Leprosy and psoriasis rarely coexist, the specific molecular mechanisms underlying their mutual exclusion have not been extensively investigated. This study aimed to reveal the underlying mechanism responsible for the mutual exclusion between psoriasis ...
You-Wang Lu +8 more
doaj +1 more source
Intestinal bacterium-derived cyp27a1 prevents colon cancer cell apoptosis.
The pathogenesis of metastasis of colon cancer (Cca) is to be further investigated. The dysfunction of apoptotic mechanism plays a role in the cancer cell over growth. This study tests a hypothesis by which intestinal bacterium-derived cyp27a1 prevents apoptosis in colon cancer cells.
Yan-Chao, Ji +5 more
openaire +1 more source
Overexpression of G6PD is associated with high risks of recurrent metastasis and poor progression-free survival in primary breast carcinoma [PDF]
core +1 more source

