Results 191 to 200 of about 47,525 (299)

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first‐pass metabolism, CYP2D6 genotype and formulation‐dependent bioavailability [PDF]

, 2003
Thomas Kerbusch, Ulrika Wählby, Peter A. Milligan, Mats O. Karlsson   +3 more
openalex   +1 more source

Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions

Journal of Evaluation in Clinical Practice, Volume 31, Issue 7, October 2025.
ABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
N. N. Ngcobo
wiley   +1 more source

How CYP2D6 Polymorphism Modulates the Community-Wide Risk of Plasmodium vivax Infection: A Panel Study in Amazonian Brazil. [PDF]

J Infect Dis
Puça MCSB, Naziazeno IM, Santos VCFD, Rodrigues PT, Calil PR, Ladeia WA, Gil JP, Ferreira MU, Nobrega De Sousa T.   +8 more
europepmc   +1 more source

CYP2D6, GST‐M1 and GST‐T1 enzymes: expression in parathyroid gland and association with the parathyroid hormone concentration during early renal replacement therapy [PDF]

, 2003
Fengxiang Yan, M. Chris Langub, Mark Ihnen, Carlton A. Hornung, Erkki Juronen, Mary Kay Rayens, Weimin Cai, Peter J. Wedlund, Paolo Fanti   +8 more
openalex   +1 more source

Enhancing CYP2D6 genotyping with nanopore sequencing to address allele diversity P. vivax malaria elimination. [PDF]

Sci Rep
Wongsurawat T, Jenjaroenpun P, Suwannasin K, Wankaew N, Sanguansakpakdee N, Amornpornviwat T, Dondorp AM, Day NPJ, Nosten F, White NJ, Imwong M.   +10 more
europepmc   +1 more source

Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction

, 2000
Rebecca Roberts, Patrick F. Sullivan, Peter R. Joyce, Martin A. Kennedy   +3 more
openalex   +1 more source

The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6 [PDF]

, 2003
Thomayant Prueksaritanont, Bennett Ma, Nathan X. Yu   +2 more
openalex   +1 more source

Impact of <i>CYP1A</i>, <i>CYP2C19</i>, <i>CYP2D6</i>, <i>CYP3A4</i>, <i>CYP3A5</i>, and <i>NFIB</i> genotypes on clozapine serum concentration in smokers and nonsmokers. [PDF]

Ther Adv Psychopharmacol
Lenk HÇ, Bråten LS, Andreassen OA, Molden E.   +3 more
europepmc   +1 more source

CYP2D6 Poor Metabolizer Status Can Be Ruled Out by a Single Genotyping Assay for the −1584G Promoter Polymorphism [PDF]

, 2003
Andrea Gaedigk, Darren L Ryder, L. DiAnne Bradford, J. Steven Leeder   +3 more
openalex   +1 more source

CYP2D6 Genotype and Primaquine Treatment in Patients with Malaria, Venezuela. [PDF]

Emerg Infect Dis
Pacheco C, Hernández-Acosta A, Pulido N, Ceballos Y, Saavedra D, Gómez C, Moreno N, Herrera F.   +7 more
europepmc   +1 more source