Results 101 to 110 of about 34,415 (185)

Comparative proteomics analysis of root and nodule mitochondria of soybean

Plant, Cell &Environment, EarlyView.
Abstract Legumes perform symbiotic nitrogen fixation through rhizobial bacteroids housed in specialised root nodules. The biochemical process is energy‐intensive and consumes a huge carbon source to generate sufficient reducing power. To maintain the symbiosis, malate is supplied by legume nodules to bacteroids as their major carbon and energy source ...
Wai‐Ching Sin, Jinhong Liu, Jia Yi Zhong, Hon‐Ming Lam, Boon Leong Lim   +4 more
wiley   +1 more source

Production of hydrogen sulfide from D-cysteine and its therapeutic potential

Frontiers in Endocrinology, 2013
Accumulating evidence shows that H2S has physiological functions in various tissues and organs. It includes regulation of neuronal activity, vascular tension, a release of insulin, and protection of the heart, kidney and brain from ischemic insult. H2S
Norihiro eShibuya, Hideo eKimura
doaj   +1 more source

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes [PDF]

, 2015
X-linked intellectual disability (XLID) is a clinically and genetically heterogeneous disorder. During the past two decades in excess of 100 X-chromosome ID genes have been identified.
A Dufke, A Frattini, A Gardner, A Hackett, A Latos-Bieleńska, A Masurel-Paulet, A Mikhailov, A P M de Brouwer, A Piton, A Piton, A Piton, A Tzschach, A van Bömmel, A-K Emde, AC Whibley, AK Emde, AK Philips, AK Vaags, AP de Brouwer, AT Vulto-van Silfhout, AT Vulto-van Silfhout, B Budny, B Echenne, B Poeck, B Simon-Bouy, BJ O'Roak, BM Neale, BS Shin, C Depienne, C Jensen, C Langnick, C Lorenz, C Mignon-Ravix, C Shoubridge, C Tan, C Vincent-Delorme, CC Homan, CD Castle, CD Castle, CE Schwartz, CH Hu, CJ Wylie, CM Hughes, CY Ou, D Kasper, D Lederer, D Steinberger, D Weese, DG MacArthur, DM Haddad, E Haan, EA Bykova, EA Oberg, ET Lim, F Laumonnier, G Annerén, G Baynam, G Froyen, G Froyen, G Gillessen-Kaesbach, G Houge, G Lesca, G Markson, G Rickheit, G Rodríguez Criado, G Strobl-Wildemann, G Turner, GD Gilfillan, GM Beaudoin 3rd, H Hirata, H Hu, H Hu, H Li, H Najmabadi, H Richard, H Risheg, H van Bokhoven, H van Bokhoven, H Van Esch, H Venselaar, H Yonath, H-H Ropers, HC Yu, HH Ropers, HP Ostendorff, HW Lee, I Bach, I Iossifov, I Longo, I Meloni, I Voineagu, I Yao, IA Adzhubei, J Boyle, J Chelly, J Gecz, J Göke, J Lee, J Lim, J Mo, J Nelson, J Ouyang, J Rucci, J Vandewalle, J-P Fryns, JJ Johnston, JK Bedoyan, JM Schwarz, JR Ecker, K Cheng, K Devriendt, K Dufu, K E P van Roozendaal, K L Friend, K Ohtakara, K Wrogemann, KR Veeramah, KS Pollard, L B Ousager, L Castelnau, L Christie, L Feng, L Huang, L Prezeau, L Van Maldergem, L Van Maldergem, LM Dibbens, M A Corbett, M Badura-Stronka, M Bienek, M Cohen, M Feldkamp, M Field, M Furukawa, M Giannandrea, M Hambrock, M Harakalova, M I Love, M Jimenez-Pocquet, M Kircher, M Poet, M Raynaud, M Raynaud, M Shaw, M Vingron, M Willemsen, M Wilson, M-L Bondeson, M-P Moizard, MA Deardorff, MA Stiffler, ME Sowa, MG Reese, MH Mokalled, MI Love, N Lebrun, N Nadif Kasri, N Ronce, O Dorseuil, O Scheel, O Scheel, P Billuart, P Cacciagli, P Fanis, P Kumar, P Starokadomskyy, P Wieacker, PS Tarpey, R Chenna, R Estévez, R Graeser, R Lehrke, R Li, R Montjean, R Sun, R Ullmann, RG Lehrke, RJ Butterfield, S A Haas, S Belet, S Claes, S G M Frints, S Hellman-Aharony, S Honda, S Jamain, S Kaech, S Makino, S O'Keeffe, S Weinert, S Willis-Owen, SH Li, SJ Hayflick, SJ Sanders, SM Stobrawa, T F Wienker, T Friedrich, T J Jentsch, T Kleefstra, T Stauber, T Stuhlmann, T Zemojtel, TS Geetha, U Fischer, U Klein, U Kornak, U Müller, V Besset, V M Kalscheuer, W Chen, W Wissink-Lindhout, WY Fu, XM Ma, Y Li, Y Liu, Y Zhao, YH Jiang, Z Iqbal   +216 more
core   +5 more sources

Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions*

Journal of Biological Chemistry, 2009
In mammals, the two enzymes in the trans-sulfuration pathway, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE), are believed to be chiefly responsible for hydrogen sulfide (H2S) biogenesis.
Sangita Singh, D. Padovani, R. Leslie, T. Chiku, R. Banerjee   +4 more
semanticscholar   +1 more source

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Homocystinuria presenting as a calcified right atrial mass

Annals of Pediatric Cardiology, 2018
Homocystinuria is a genetic inborn error of metabolism due to the deficiency of cystathionine β-synthase resulting in increased serum homocysteine and methionine and decreased cysteine which predisposes affected individuals to arterial and venous ...
Tahleel Altaf Shera, Naseer Ahmed Choh, Faiz Altaf Shera, Azher Maqbool Khan   +3 more
doaj   +1 more source

Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S [PDF]

, 2014
Activation of plasma membrane TGR5 receptors in enteroendocrine cells by bile acids is known to regulate gastrointestinal secretion and motility and glucose homeostasis.
Ancy D. Nalli, Arun J. Sanyal, Divya P. Kumar, John R. Grider, Karnam S. Murthy, Senthilkumar Rajagopal, Sunila Mahavadi, Vanitha Bala   +7 more
core   +2 more sources

Sodium thiosulfate treatment rescues hyperglycaemia‐induced pronephros damage in zebrafish by upregulating nitric oxide signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott, Katrin Bennewitz, Xin Zhang, Mariia Prianichnikova, Carsten Sticht, Gernot Poschet, Jens Kroll   +6 more
wiley   +1 more source

Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism [PDF]

, 2019
Elaborate antioxidant pathways have evolved to minimize the threat of excessive reactive oxygen species (ROS) and to regulate ROS as signaling entities.
Gao, Yan, Olson, Kenneth R.
core   +1 more source

Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond

Journal of Biological Chemistry, 2018
Cystathionine β-synthase (CBS) is the central enzyme in the trans-sulfuration pathway that converts homocysteine to cysteine. It is also one of the three major enzymes involved in the biogenesis of H2S.
W. Niu, Jun Wang, J. Qian, Mengying Wang, P. Wu, Fei Chen, Shasha Yan   +6 more
semanticscholar   +1 more source