Results 51 to 60 of about 1,104,559 (168)

Supplemental Material, CBS-CATH-Table_1S,_2S - Association of Cystathionine β-Synthase Gene Polymorphisms With Preeclampsia

, 2018
Supplemental Material, CBS-CATH-Table_1S,_2S for Association of Cystathionine β-Synthase Gene Polymorphisms With Preeclampsia by Mercedes de León Bautista, Mirza Romero-Valdovinos, Beatriz Zavaleta-Villa, Arony Martínez-Flores, and Angélica Olivo-Díaz in
Beatriz Zavaleta-Villa (5965601), Angélica Olivo-Díaz (5965607), Mercedes de León Bautista (5965598), Mirza Romero-Valdovinos (708151), Arony Martínez-Flores (5965604)   +4 more
core   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

British Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam, Hongyuan Zhang, Min Zi, Chen Chen, Junfang Wu, Andreas Papapetropoulos, Xin Wang   +6 more
wiley   +1 more source

Antitumor effect of sikokianin C, a selective cystathionine β-synthase inhibitor, against human colon cancer in vitro and in vivo

, 2018
A natural biflavonoid compound, sikokianin C, which is a selective, competitive inhibitor of cystathionine β-synthase, inhibits the proliferation and growth of colon cancer cells in vitro and in vivo.
Jing Qian, Jun Wang, Fei Chen, Weining Niu, Shasha Yan   +4 more
core   +1 more source

HOAs are present in diverse fungal pathogens but absent in their gramineous hosts.

, 2023
The heat map shows the gene number of the key enzymes in the biosynthesis of methionine in fungi and plants examined. CBL, cystathionine β-lyase. CBS, cystathionine β-synthase. CGL, cystathionine γ-lyase. CGS, cystathionine γ-synthase.
Leiyun Yang (2636971), Zhengguang Zhang (190550), Jun Zhang (48506), Xinyu Liu (34266), Zhuoer Xie (7289042), Haifeng Zhang (137541), Ping Wang (42415), Han Chen (228557), Muxing Liu (716957), Huimin Li (126429), Pengcheng Mo (17020969)   +10 more
core   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

The FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal, Žaneta Zajacová, Rick Oerlemans, Jana Havlikova, Gabriel Zorkócy, Lukáš Kerti, Katarína Sujová, Adrian Lengyel, Zoë van der Gun, Christina Yoseif, Adrianus Cornelis van der Graaf, Guido Krenning, Ján Kyselovič, Vladimír Frecer, Matthew R. Groves, Zdenko Levarski, André Heeres, Rob H. Henning, Leo E. Deelman   +18 more
wiley   +1 more source

Caracterização molecular da enzima cistationina β-sintase (cβs) em Trypanosoma rangeli [PDF]

, 2014
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Trypanosoma rangeli é um parasitos hemoflagelados que infecta insetos e mamíferos. Possuem um sistema de resposta antioxidante baseada no ditiol tripanotiona
Yamanaka, Lais Eiko
core  

Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain ...
Mervin Chun‐Yi Ang, Jolly Madathiparambil Saju, Sayyid Mohaideen, Niha Dhar, Sarangapani Sreelatha, Sayuj Koyyappurath, Thomas K. Porter, Gabriel Sánchez‐Velázquez, Vaishnavi Reddy Amarr, Song Wang, Duc Thinh Khong, Suh In Loh, Michael S. Strano, Sarojam Rajani   +13 more
wiley   +1 more source

Crystal structure of cystathionine β-synthase from honeybee Apis mellifera

, 2019
Cystathionine β-synthase (CBS), the key enzyme in the transsulfuration pathway, links methionine metabolismto the biosynthesis of cellular redox controlling molecules.
Juraj Majtán (427560), Paula Gimenez-Mascarell (6440425), Iker Oyenarte (6440426), Jaroslav Klaudiny (6440429), Jan P. Kraus (6422100), Luis Alfonso Martínez-Cruz (2384026), June Ereno-Orbea (6428827), Tomas Majtan (6422097)   +7 more
core   +1 more source

Cystathionine β -Synthase in Physiology and Cancer [PDF]

, 2018
Cystathionine β-synthase (CBS) regulates homocysteine metabolism and contributes to hydrogen sulfide (H2S) biosynthesis through which it plays multifunctional roles in the regulation of cellular energetics, redox status, DNA methylation, and protein ...
Chan, KT, Kang, J, Pearson, Richard B., Zhu, Haoran, Blake, S, Blake, Shaun, Chan, Keefe T., Zhu, H, Pearson, RB, Kang, Jian   +9 more
core   +1 more source