Results 41 to 50 of about 1,104,559 (168)

MOESM1 of Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

, 2018
Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug ...
Bartosz Szczesny (16538), Amy Mrazek (5816378), Nadiya Druzhyna (5816381), Celia Chao (525874), John Zatarain (5816372), Mark Hellmich (5816405), Kazunori Yanagi (2364097), Gabor Olah (459086), Paul Johnson (350591), Jia Zhou (53252), Ciro Coletta (5816375), Akbar Ahmad (395893), Judy Hellmich (5816384), Gabor Törö (5816390), David Eckelbarger (5816399), Rachel Lewis (246649), Katalin Módis (422088), Minal Cheema (5816396), Fredrick Bohanon (5816393), Haiying Chen (9771), Csaba Szabo (422091), Petra Szoleczky (422087), Antonia Asimakopoulou (5816387), Ye Ding (40594), Andreas Papapetropoulos (77896), Ashley Untereiner (5816402)   +25 more
core   +1 more source

Molecular characterization of a cystathionine beta-synthase gene, CBS1, in Magnaporthe grisea [PDF]

, 2002
CBS1 from Magnaporthe grisea is a structural and functional homolog of the cystathionine β-synthase (CBS) gene from Saccharomyces cerevisiae. Our studies indicated that M.
Hamer, L, Lo, SCC, Hamer, JE
core   +1 more source

Hydrogen Sulfide Levels and Nuclear Factor‐Erythroid 2‐Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Cystathionine γ‐lyase, cystathionine β‐synthase, and 3‐mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H2S).
Kazi N. Islam, David J. Polhemus, Erminia Donnarumma, Luke P. Brewster, David J. Lefer   +4 more
doaj   +1 more source

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

Biology Open, 2015
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide.
Hua Jiang, K. Joseph Hurt, Kelsey Breen, Sally P. Stabler, Robert H. Allen, David J. Orlicky, Kenneth N. Maclean   +6 more
doaj   +1 more source

The intact structure of Candida albicans cystathionine β-synthase through homology modeling

, 2020
The crystal structure of the catalytic core of C. albicans cystathionine β-synthase (cCBS-cc, residues 1-319) was obtained by us (PDB accession code：6KV4). However, the whole structure of C.
Wenqiang Chang (8518254)
core   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

The effects of hydrogen sulfide synthesis inhibition in lindane-induced seizures in rats: A behavioral and EEG study [PDF]

Archives of Biological Sciences, 2020
Lindane-induced seizure in rats is a model of refractory generalized epilepsy. Hydrogen sulfide (H2S) is a gasotransmitter with different physiological and pathological roles.
Šutulović Nikola, Rašić-Marković Aleksandra, Grubač Željko, Đurić Emilija, Hrnčić Dragan   +4 more
doaj   +1 more source

Hydrogen sulfide mitigates skeletal muscle mitophagy‐led tissue remodeling via epigenetic regulation of the gene writer and eraser function

Physiological Reports, 2022
Ketone bodies (KB) serve as the food for mitochondrial biogenetics. Interestingly, probiotics are known to promote KB formation in the gut (especially those that belong to the Lactobacillus genus).
Mahavir Singh, Sathnur Pushpakumar, Yuting Zheng, Rubens P. Homme, Irina Smolenkova, Sri Prakash L. Mokshagundam, Suresh C. Tyagi   +6 more
doaj   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source