Scientific Reports, 2023 Hydrogen sulfide (H2S) is a gaseous signaling molecule that participates in various signaling functions in health and diseases. The tetrameric cystathionine γ-lyase (CSE) contributes to H2S biogenesis and several investigations provide evidence on the ...
Laurent Le Corre, Dominique Padovani
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Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii [PDF]
, 2018 Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes ...
Astegno, A. +6 more
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Influence of sex hormones on DNA content and cystathionine-γ-lyase expression in rat myocardium
Zaporožskij Medicinskij Žurnal, 2017 Till now sexual features of cystathionine-γ-lyase/H2S system functioning in heart and its relationship to DNA content in myocardial cells nuclei depending on the level of sex hormones.
A. V. Melnik +4 more
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LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
, 2014 The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart +7 more
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Divergent behavior of hydrogen sulfide pools and of the sulfur metabolite lanthionine, a novel uremic toxin, in dialysis patients. [PDF]
, 2016 Dialysis patients display a high cardiovascular mortality, the causes of which are still not completely explained, but are related to uremic toxicity.
Amoresano, A +10 more
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BMC Cancer, 2018 Background Knowledge about the expression and thus a role of enzymes that produce endogenous H2S - cystathionine-β-synthase, cystathionine γ-lyase and mercaptopyruvate sulfurtransferase - in renal tumors is still controversial.
Jan Breza +11 more
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Enhanced expression of cystathionine β-synthase and cystathionine γ-lyase during acute cholecystitis-induced gallbladder inflammation. [PDF]
PLoS ONE, 2013 BACKGROUND: Hydrogen sulfide (H2S) has recently been shown to play an important role in the digestive system, but the role of endogenous H2S produced locally in the gallbladder is unknown.
Li Zhang +4 more
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Cellular and Molecular Gastroenterology and Hepatology, 2018 Hydrogen sulfide (H2S) is a major physiologic gastrotransmitter. Its role in the regulation of the lower esophageal sphincter (LES) function remains unknown. The present study addresses this question.
Xiaopeng Bai +11 more
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Screening, morphological and molecular characterization of fungi producing cystathionine γ-lyase [PDF]
, 2015 The potency for production of cystathionine γ-lyase (CGL) by the fungal isolates was screened. Among the tested twenty-two isolates, Aspergillus carneus was the potent CGL producer (6.29 U/mg), followed by A. ochraceous (6.03 U/mg), A. versicolor (2.51 U/
Abdel-Hamid, Gamal +3 more
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Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of
BMC Research Notes, 2012 Background Cystathionine γ-lyase plays a key role in the transsulfuration pathway through its primary reaction of catalyzing the formation of cysteine from cystathionine.
Reveal Brad S, Paietta John V
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