Results 111 to 120 of about 7,369 (184)
The anti-proliferative and anti-inflammatory response of COPD airway smooth muscle cells to hydrogen sulfide [PDF]
, 2018 BACKBROUND: COPD is a common, highly debilitating disease of the airways, primarily caused by smoking. Chronic inflammation and structural remodelling are key pathological features of this disease caused, in part, by the aberrant function of airway ...
Adcock, Ian +8 more
core +1 more source
Exogenous H2S Regulates of Cystathionine Gamma-Lyase in HUVECs During Hypoxia
, 2020 Cystathionine gamma-lyase (CSE) is one of the essential H2S-producing enzymes, and it regulates diverse functions in connection with cardiovascular function. It is crucial how exogenous H2S regulates CSE expression of the vascular endothelial cell during hypoxia.
openaire +2 more sources
, 2009 The endothelium controls vascular tone not only by releasing NO and prostacyclin, but also by other pathways causing hyperpolarization of the underlying smooth muscle cells.
Félétou, M, VanHoutte, PM
core +1 more source
Cellular Physiology and Biochemistry, 2015 Aims: Hydrogen sulfide (H2S) inhibits the proliferation of vascular smooth muscle cells (VSMCs). However, how cystathionine-gamma-lyase (CSE), a major enzyme that produces H2S, is regulated remains unknown.
Xin Zhong +13 more
doaj +1 more source
Identification of probasin-related antigen as cystathionine gamma-lyase by molecular cloning.
Journal of Biological Chemistry, 1994 We reported previously that a monoclonal antibody against probasin (rat prostatic secretory protein) recognizes a 40-kDa protein localized in rat liver and kidney. The protein (probasin-related antigen, PRB-RA) may participate in a specific differentiated function of these tissues.
N, Nishi +5 more
openaire +2 more sources
Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system. [PDF]
, 2017 There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two ...
Bucci, M., Cirino, G, Vellecco, V
core +1 more source
Redox Biology, 2017 The molecular and cellular mechanisms underlying plaque destabilization remain obscure. We sought to elucidate the correlation between NO, H2S and CO-generating enzymes, nitro-oxidative stress and plaque stability in carotid arteries.
Fragiska Sigala +8 more
doaj +1 more source
Characteristics of the tomato chromoplast revealed by proteomic analysis [PDF]
, 2010 Chromoplasts are non-photosynthetic specialized plastids that are important in ripening tomato fruit (Solanum lycopersicum) since, among other functions, they are the site of accumulation of coloured compounds.
Barsan, Cristina +9 more
core +3 more sources
Pharmacological ResearchHydrogen sulfide (H₂S), a gasotransmitter naturally produced in the body by enzymes such as cystathionine γ lyase (CSE), helps reduce inflammation, oxidative stress, and abnormal tissue calcification.
Sonia Nasi +11 more
doaj +1 more source
Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features [PDF]
, 2016 Mutations that cause neurological phenotypes are highly informative with regard to mechanisms governing human brain function and disease. We report autosomal recessive mutations in the enzyme glutamate pyruvate transaminase 2 (GPT2) in large kindreds ...
Al-Saffar, Muna +28 more
core +1 more source