Cystathionine gamma-lyase as an inflammatory factor and its link with immune inflammation in hepatitis B virus-related liver disease [PDF]
Scientific ReportsWe aimed to explore the effectiveness of CTH as a serum inflammation biomarker for HCC. Enzyme-linked immunosorbent assay was used to detect serum levels of CTH, interleukin-6 (IL-6), C-reactive protein (CRP), and IL-10.
Chao Jin +5 more
doaj +2 more sources
Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in ...
Seyyed Ali Mard +3 more
doaj +1 more source
Cystathionine gamma lyase and hydrogen sulfide: new players in orthodontic root resorption. [PDF]
Ann Transl Med, 2020 Holliday LS, Dolce C.
europepmc +3 more sources
Cystathionine gamma-lyase expression is regulated by exogenous hydrogen peroxide in the mammalian cells. [PDF]
Gene Expr, 2012 Hydrogen sulfide (H2S), as an endogenous signaling molecule in mammals, shows a variety of biological effects. Cystathionine gamma-lyase (CSE)/H2S pathway has been implicated in scavenging reactive oxygen species (ROS) in the mammalian cells. Therefore, we first investigated the regulatory effects of exogenously applied hydrogen peroxide (H2O2) on CSE ...
Wang M, Guo Z, Wang S.
europepmc +4 more sources
Role of 3-Mercaptopyruvate Sulfurtransferase (3-MST) in Physiology and Disease
Antioxidants, 2023 3-mercaptopyruvate sulfurtransferase (3-MST) plays the important role of producing hydrogen sulfide. Conserved from bacteria to Mammalia, this enzyme is localized in mitochondria as well as the cytoplasm. 3-MST mediates the reaction of 3-mercaptopyruvate
Swetha Pavani Rao +3 more
doaj +1 more source
Cystathione gamma lyase/hydrogen sulphide pathway up regulation enhances the responsiveness of ?1A and ?1B-adrenoreceptors in the kidney of rats with left ventricular hypertrophy [PDF]
, 2016 The purpose of the present study was to investigate the interaction between H2S and NO (nitric oxide) in the kidney and to evaluate its impact on the functional contribution of ?1A and ?1B-adrenoreceptors subtypes mediating the renal vasoconstriction in ...
Abdulla, Mohammed H. +7 more
core +19 more sources
Role of Cystathionine Gamma-Lyase in Immediate Renal Impairment and Inflammatory Response in Acute Ischemic Kidney Injury. [PDF]
Sci Rep, 2016 Hydrogen sulfide (H2S) is known to act protectively during renal ischemia/reperfusion injury (IRI). However, the role of the endogenous H2S in acute kidney injury (AKI) is largely unclear.
Markó L +12 more
europepmc +4 more sources
Endogenous Hydrogen Sulfide Is an Important Factor in Maintaining Arterial Oxygen Saturation
Frontiers in Pharmacology, 2021 The gasotransmitter H2S is involved in various physiological and pathophysiological processes. The aim of this study was to investigate the physiological functions of H2S in the lungs.
Yan Huang +11 more
doaj +1 more source
The Role of Hydrogen Sulfide in Plaque Stability
Antioxidants, 2022 Atherosclerosis is the greatest contributor to cardiovascular events and is involved in the majority of deaths worldwide. Plaque rapture or erosion precipitates life-threatening thrombi, resulting in the obstruction blood flow to the heart (acute ...
Qian Lin, Bin Geng
doaj +1 more source
Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells [PDF]
Cardiovascular Research, 2010 Cystathionine gamma-lyase (CSE)-derived H2S plays an important role in regulating cell growth. Lack of CSE expression results in development of hypertension. The current study compared proliferation of smooth muscle cells derived from CSE gene knockout mice (SMCs-KO) with that of wild-type mice (SMCs-WT).Cell proliferation was assessed by ...
Guangdong, Yang +5 more
openaire +2 more sources