Results 31 to 40 of about 7,369 (184)
Hydrogen sulfide pathway and skeletal muscle: an introductory review. [PDF]
, 2018 The presence of the H2 S pathway in skeletal muscle (SKM) has recently been established. SKM expresses the three constitutive H2 S-generating enzymes in animals and humans, and it actively produces H2 S.
Armogida Chiara +2 more
core +4 more sources
Redox Biology, 2020 Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
Sergio Rius-Pérez +11 more
doaj +1 more source
Redox Biology, 2022 Reactive sulfur species (RSS) play a role in redox homeostasis; however, adaptive cell responses to excessive intracellular RSS are not well understood. Therefore, in this study, we generated transgenic (Tg) mice overexpressing cystathionine gamma-lyase (
Masahiro Akiyama +11 more
doaj +1 more source
Scientific Reports, 2021 Ginseng (Panax ginseng Meyer) is commonly used as an herbal remedy worldwide. Few studies have explored the possible physiological changes in the liver although patients often self-medicate with ginseng preparations, which may lead to exceeding the ...
Ann-Yae Na +8 more
doaj +1 more source
Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
eLife, 2021 A fundamental challenge in human immunodeficiency virus (HIV) eradication is to understand how the virus establishes latency, maintains stable cellular reservoirs, and promotes rebound upon interruption of antiretroviral therapy (ART).
Virender Kumar Pal +6 more
doaj +1 more source
The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]
, 2009 Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Carson, Ray J. +4 more
core +5 more sources
Effects of simultaneous pharmacological inhibition of cystathionine gamma-lyase and nitric oxide synthase on food and water intake, body mass gain, and body temperature in rats [PDF]
Journal of Biomedical & Clinical ResearchVarious studies have emphasized the intricate relationship between hydrogen sulfide (H2S) and nitric oxide (NO) in regulating diverse physiological processes.
Milen Hristov, Pavlina Andreeva-Gateva
doaj +3 more sources
Functional characterization and structure-guided mutational analysis of the transsulfuration enzyme cystathionine γ-lyase from toxoplasma gondii [PDF]
, 2018 Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes ...
Astegno, A. +6 more
core +2 more sources
Acta Physiologica, 2023 AbstractAimIn extracerebral vascular beds cystathionine‐gamma lyase (CSE) activity plays a vasodilatory role but the role of this hydrogen sulfide (H2S) producing enzyme in the intracerebral arterioles remain poorly understood. We hypothesized a similar function in the intracerebral arterioles.MethodsIntracerebral arterioles were isolated from wild ...
Maria Peleli +5 more
openaire +4 more sources
The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues [PDF]
, 2011 The enzymes of the transsulfuration pathway, cystathionine --synthase (CBS) and cystathionine --lyase (CSE), are important for the endogenous production of hydrogen sulfide (H2S), a gaseous signaling molecule. The relative contributions of CBS and CSE to
Kery V +6 more
core +1 more source