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Biochimie, 2010
Plant cystatins have been the object of intense research since the publication of a first paper reporting their existence more than 20 years ago. These ubiquitous inhibitors of Cys proteases play several important roles in plants, from the control of various physiological and cellular processes in planta to the inhibition of exogenous Cys proteases ...
Dominique Michaud +2 more
exaly +3 more sources
Plant cystatins have been the object of intense research since the publication of a first paper reporting their existence more than 20 years ago. These ubiquitous inhibitors of Cys proteases play several important roles in plants, from the control of various physiological and cellular processes in planta to the inhibition of exogenous Cys proteases ...
Dominique Michaud +2 more
exaly +3 more sources
Cystatins in Health and Diseases [PDF]
International Journal of Peptide Research and Therapeutics, 2008 The Cystatins constitute a large group of evolutionary related proteins with diverse biological activities. They have been recently realized as instrumental in myriad of pathophysiological conditions. They have been implicated in various pathological conditions.
Bilqees Bano
exaly +3 more sources
Recombinant cystatins in plants
Biochimie, 2019Dozens of studies have assessed the practical value of plant cystatins as ectopic inhibitors of Cys proteases in biological systems. The potential of these proteins in crop protection to control herbivorous pests and pathogens has been documented extensively over the past 25 years.
Dominique Michaud, Marie-Claire Goulet
exaly +3 more sources
Biochemical Society Symposia, 2003
Chicken egg white cystatin was first described in the late 1960s. Since then, our knowledge about a superfamily of similar proteins present in mammals, birds, fish, insects, plants and some protozoa has expanded, and their properties as potent peptidase inhibitors have been firmly established.
Magnus, Abrahamson +2 more
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Chicken egg white cystatin was first described in the late 1960s. Since then, our knowledge about a superfamily of similar proteins present in mammals, birds, fish, insects, plants and some protozoa has expanded, and their properties as potent peptidase inhibitors have been firmly established.
Magnus, Abrahamson +2 more
openaire +2 more sources
Deleterious effects of plant cystatins against the banana weevil Cosmopolites sordidus [PDF]
Archives of Insect Biochemistry and Physiology, 2010 The general potential of plant cystatins for the development of insect-resistant transgenic plants still remains to be established given the natural ability of several insects to compensate for the loss of active cysteine proteases following inhibitor ...
Christell van der Vyver +2 more
exaly +2 more sources
Cystatins S and C in Human Whole Saliva and in Glandular Salivas in Periodontal Health and Disease
Journal of Dental Research, 1994 Cystatins are inhibitors of cysteine proteinases and could play a protective and regulatory role under inflammatory conditions. Since total cystatin activity of whole saliva was increased in periodontal patients (Henskens et al., 1993), we wanted to ...
E C I Veerman +2 more
exaly +2 more sources
Family 2 cystatins inhibit osteoclast-mediated bone resorption in calvarial bone explants
Bone, 2004 Osteoclastic bone resorption depends on the activity of various proteolytic enzymes, in particular those belonging to the group of cysteme protemases. Biochemical studies have shown that cystatins, naturally occurring inhibitors of these enzymes, inhibit
Wouter Beertsen +2 more
exaly +2 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2002
Clinical biochemists have long known the analytical and clinical limitations of creatinine and creatinine clearance measurement in the assessment of glomerular filtration rate (GFR). This background is reviewed in the article before assessing the utility of cystatin C, the most promising replacement biochemical marker yet identified.
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Clinical biochemists have long known the analytical and clinical limitations of creatinine and creatinine clearance measurement in the assessment of glomerular filtration rate (GFR). This background is reviewed in the article before assessing the utility of cystatin C, the most promising replacement biochemical marker yet identified.
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The Journal of Biochemistry, 1991
Our recent work on the gene structures for human salivary (S-type) cystatins [Saitoh, E. et al. (1987) Gene 61, 329-338] has suggested that the structures of cystatins which we determined previously at the protein level lack N-terminal peptide portions of the full-sized intact forms. In the present study, attempts were made to isolate full-sized S-type
S, Isemura +3 more
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Our recent work on the gene structures for human salivary (S-type) cystatins [Saitoh, E. et al. (1987) Gene 61, 329-338] has suggested that the structures of cystatins which we determined previously at the protein level lack N-terminal peptide portions of the full-sized intact forms. In the present study, attempts were made to isolate full-sized S-type
S, Isemura +3 more
openaire +2 more sources
Cystatins of Parasitic Organisms
2011The cystatin superfamily comprises several groups of protease inhibitors. In this chapter we will focus on I25 family members, which consist predominantly of the type 2 cystatins. Recently, a wealth of information on these molecules and their activities has been described.
Christian, Klotz +3 more
openaire +2 more sources