Results 11 to 20 of about 589,705 (297)

A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD

Molecules, 2023
CAD is a 1.5 MDa hexameric protein with four enzymatic domains responsible for initiating de novo biosynthesis of pyrimidines nucleotides: glutaminase, carbamoyl phosphate synthetase, aspartate transcarbamoylase (ATC), and dihydroorotase.
Francisco del Caño-Ochoa, Antonio Rubio-del-Campo, Santiago Ramón-Maiques   +2 more
doaj   +1 more source

Preventing Developmental Origins of Cardiovascular Disease: Hydrogen Sulfide as a Potential Target?

Antioxidants, 2021
The cardiovascular system can be programmed by a diversity of early-life insults, leading to cardiovascular disease (CVD) in adulthood. This notion is now termed developmental origins of health and disease (DOHaD).
Chien-Ning Hsu, You-Lin Tain
doaj   +1 more source

Viral cysteine proteinases [PDF]

Perspectives in Drug Discovery and Design, 1996
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly related to papain or chymotrypsin and may be direct descendants of primordial proteolytic enzymes.
Gorbalenya, Alexander E., Snijder, Eric J.   +1 more
openaire   +2 more sources

Toward Food Freshness Monitoring: Coordination Binding–Based Colorimetric Sensor Array for Sulfur-Containing Amino Acids

Frontiers in Chemistry, 2021
Herein, a self-assembled colorimetric chemosensor array composed of off-the-shelf catechol dyes and a metal ion (i.e., Zn2+) has been used for the sulfur-containing amino acids (SCAAs; i.e., glutathione, glutathione disulfide, L–cysteine, DL–homocysteine,
Xiaojun Lyu, Wei Tang, Yui Sasaki, Jie Zhao, Tingting Zheng, Yang Tian, Tsuyoshi Minami   +6 more
doaj   +1 more source

Transcriptome Analysis of Maize Immature Embryos Reveals the Roles of Cysteine in Improving Agrobacterium Infection Efficiency

Frontiers in Plant Science, 2017
Maize Agrobacterium-mediated transformation efficiency has been greatly improved in recent years. Antioxidants, such as, cysteine, can significantly improve maize transformation frequency through improving the Agrobacterium infection efficiency. However,
Yan Liu, Yan Liu, Zhiqiang Zhang, Zhiqiang Zhang, Junjie Fu, Guoying Wang, Jianhua Wang, Yunjun Liu   +7 more
doaj   +1 more source

Interactive Effects of Glycine Equivalent, Cysteine, and Choline on Growth Performance, Nitrogen Excretion Characteristics, and Plasma Metabolites of Broiler Chickens Using Neural Networks Optimized with Genetic Algorithms

Animals, 2020
Responses of broiler chickens to dietary glycine equivalent (Glyequi) are affected by dietary cysteine and choline. Hence, this study investigated interactive effects among dietary Glyequi, cysteine, and choline on the growth of broiler chickens.
Philipp Hofmann, Wolfgang Siegert, Hamed Ahmadi, Jochen Krieg, Moritz Novotny, Victor D. Naranjo, Markus Rodehutscord   +6 more
doaj   +1 more source

Therapeutic Applications of Cysteamine and Cystamine in Neurodegenerative and Neuropsychiatric Diseases

Frontiers in Neurology, 2019
Current medications for neurodegenerative and neuropsychiatric diseases such as Alzheimer's disease (AD), Huntington's disease (HD), Parkinson's disease (PD), and Schizophrenia mainly target disease symptoms.
Bindu D. Paul, Solomon H. Snyder, Solomon H. Snyder, Solomon H. Snyder   +3 more
doaj   +1 more source

Effects of the substitution of amino acid residues, through chemical synthesis, on the conformation and activity of antimicrobial peptides

Orbital: The Electronic Journal of Chemistry, 2012
Antimicrobial peptides make up an assorted group of molecules which contain from 12 to 50 amino acid residues and which may be produced by microorganisms, plants and animals.
Regina C. Adão, Victor Hugo O. Munhoz, Bianca Matos Oliveira Mendes, Jarbas M. Resende, Dorila Piló-Veloso   +4 more
doaj   +1 more source

Biological Mechanisms of S-Nitrosothiol Formation and Degradation: How Is Specificity of S-Nitrosylation Achieved?

Antioxidants, 2021
The modification of protein cysteine residues underlies some of the diverse biological functions of nitric oxide (NO) in physiology and disease. The formation of stable nitrosothiols occurs under biologically relevant conditions and time scales. However,
Christopher M. Massa, Ziping Liu, Sheryse Taylor, Ashley P. Pettit, Marena N. Stakheyeva, Elena Korotkova, Valentina Popova, Elena N. Atochina-Vasserman, Andrew J. Gow   +8 more
doaj   +1 more source

Comparative effects of coconut water and N-Acetyl cysteine on the hypothalamo-pituitary-gonadal axis of male rats [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2017
Coconut water (CW) contains cysteine, an amino acid which influences glutathione metabolism and promotes reproductive functions. The effects of CW and N-acetyl cysteine (NAC) were compared on the hypothalamo-pituitary-gonadal-axis of danazol-(a GnRH ...
Olufadekemi Tolulope Kunle-Alabi, Opeyemi Oreofe Akindele, Maximillian I. Odoh, Bright Onome Oghenetega, Yinusa Raji   +4 more
doaj   +1 more source